Calmodulin-like protein MdCML15 interacts with MdBT2 to modulate iron homeostasis in apple

文献类型： 外文期刊

第一作者： Liu, Xiao-Juan

作者： Liu, Xiao-Juan;Liu, Xin;Zhao, Qiang;Dong, Yuan-Hua;Yao, Yu-Xin;You, Chun-Xiang;Kang, Hui;Wang, Xiao-Fei;Liu, Xiao-Juan;Xue, Yuan;Liu, Xin;Zhao, Qiang;Liu, Qiangbo

作者机构：

期刊名称：HORTICULTURE RESEARCH （ 影响因子：7.6； 五年影响因子：8.2 ）

ISSN： 2662-6810

年卷期： 2024 年 11 卷 5 期

页码：

收录情况： SCI

摘要： BTB and TAZ domain proteins (BTs) function as specialized adaptors facilitating substrate recognition of the CUL3-RING ubiquitin ligase (CRL3) complex that targets proteins for ubiquitination in reaction to diverse pressures. Nonetheless, knowledge of the molecular mechanisms by which the apple scaffold protein MdBT2 responds to external and internal signals is limited. Here we demonstrate that a putative Ca 2+ sensor, calmodulin-like 15 (MdCML15), acts as an upstream regulator of MdBT2 to negatively modulate its functions in plasma membrane H+-ATPase regulation and iron deficiency tolerance. MdCML15 was identified to be substantially linked to MdBT2, and to result in the ubiquitination and degradation of the MdBT2 target protein MdbHLH104. Consequently, MdCML15 repressed the MdbHLH104 target, MdAHA8's expression, reducing levels of a specific membrane H+-ATPase. Finally, the phenotype of transgenic apple plantlets and calli demonstrated that MdCML15 modulates membrane H+-ATPase-produced rhizosphere pH lowering alongside iron homeostasis through an MdCML15-MdBT2-MdbHLH104-MdAHA8 pathway. Our results provide new insights into the relationship between Ca2+ signaling and iron homeostasis.

分类号：

  • 相关文献
作者其他论文 更多>>
  • Metabolomics and ionomics reveal the quality differences among peach, acacia and karaya gums

    作者：Zhang, Kaiwei;Yu, Xiangyang;Zhang, Kaiwei;Chen, Meng;Zhang, Xue;Chen, Jian;Chen, Xiaolong;Li, Yong;Yu, Xiangyang;Zhang, Kaiwei;Chen, Meng;Zhang, Xue;Chen, Jian;Chen, Xiaolong;Li, Yong;Yu, Xiangyang;Liu, Xin

    关键词：Gum; Metabolomics; Flavonoids; Total phenols content; Metabolites

  • Ustiloxin A impairs oocyte quality by disrupting organelles function

    作者：Han, Jun;Wang, Gang;Liu, Xin;Zhou, You;Hu, Junqiang;Shi, Jianrong;Xu, Jianhong;Wu, Yuzhuo;Shi, Jianrong;Xu, Jianhong;Wang, Weikang

    关键词：UA; Oocyte maturation; Mitochondria; Oxidative stress; Autophagy

  • Single-cell transcriptome atlas of lamprey exploring Natterin- induced white adipose tissue browning

    作者：Pang, Yue;Du, Zeyu;Zhang, Jin;Lu, Jiali;Li, Jun;Dong, Xinrui;Zhao, Zhisheng;Chuan, Shunqin;Sun, Mingjie;Li, Qingwei;Pang, Yue;Du, Zeyu;Zhang, Jin;Lu, Jiali;Li, Jun;Dong, Xinrui;Zhao, Zhisheng;Chuan, Shunqin;Sun, Mingjie;Li, Qingwei;Qin, Yating;Liu, Qun;Han, Kai;Yuan, Zengbao;Pan, Shanshan;Xu, Mengyang;Wang, Dantong;Li, Zhen;Chen, Yadong;Song, Yue;Zhan, Liping;Cui, Wei;Wang, Jun;Fan, Guangyi;Qin, Yating;Liu, Qun;Han, Kai;Fan, Guangyi;Qin, Yating;Liu, Qun;Han, Kai;Song, Yue;Qin, Yating;Fan, Guangyi;Yuan, Zengbao;Xu, Mengyang;Wang, Dantong;Gu, Ying;Yang, Huanming;Xu, Xun;Liu, Xin;Fan, Guangyi;Xu, Mengyang;Fan, Guangyi;Li, Shuo;Zhang, Zhe;Ni, Ming;Jia, Xiaodong;Xia, Zhangyong;Yue, Zhen;Fan, Guangyi;Gu, Ying;Yang, Huanming;Xu, Xun;Liu, Xin

    关键词：

  • PbMADS49 Regulates Lignification During Stone Cell Development in 'Dangshansuli' (Pyrus bretschneideri) Fruit

    作者：Meng, Dandan;Liu, Xin;Cai, Yongping;Meng, Dandan;Duan, Jinsheng;Meng, Dandan;Duan, Jinsheng;Cao, Yunpeng

    关键词：pear; stone cell development; lignin biosynthesis; PbMADS49; PbPRX33

  • Molecular mechanism of potently neutralizing human monoclonal antibodies against severe fever with thrombocytopenia virus infection

    作者：Quan, Chuansong;Nie, Kaixiao;Zheng, Wenjun;Wang, Yiwen;Quan, Chuansong;Zhang, Hong;Quan, Chuansong;Ma, Dezhen;Su, Chao;Li, Lianfeng;Peng, Dingkun;Yin, Chunhong;Yang, Peipei;Shan, Chao;Liu, Xin;Zheng, Jie;Shi, Weifeng;Li, Weiwei;Gao, George F.;Qi, Jianxun;Liu, Weixiao;Liu, Di;Carr, Michael J.;Carr, Michael J.;Shi, Weifeng

    关键词：severe fever with thrombocytopenia syndrome; SFTSV; Bandavirus dabieense; monoclonal antibodies; neutralization; therapeutics

  • A Novel Approach for Maize Straw Type Recognition Based on UAV Imagery Integrating Height, Shape, and Spectral Information

    作者：Liu, Xin;Gong, Huili;Guo, Lin;Zhou, Jingping;Gong, Huili;Guo, Lin;Gong, Huili;Guo, Lin;Gong, Huili;Guo, Lin;Gong, Huili;Guo, Lin;Gu, Xiaohe;Zhou, Jingping

    关键词：maize straw type; multispectral imagery; SESI; object-oriented classification; UAV

  • Host-Adaptive Divergence Shapes the Genetic Architecture of Magnaporthe oryzae in Southern China's Rice Agroecosystems

    作者：Liu, Xin;Fu, Jun;Deng, Zhao;Chen, Xinwei;Hu, Xiaochun;Tu, Zhouyi;Wang, Qiuyi;Zhu, Yuxuan;Chen, Pengcheng;Bai, Zhenan;Liu, Tiangang;Zhang, Xuanwen;Qin, Peng;Wang, Kai;Jiang, Nan;Yang, Yuanzhu;Liu, Xin;Fu, Jun;Deng, Zhao;Chen, Xinwei;Hu, Xiaochun;Tu, Zhouyi;Wang, Qiuyi;Zhu, Yuxuan;Chen, Pengcheng;Bai, Zhenan;Liu, Tiangang;Zhang, Xuanwen;Qin, Peng;Wang, Kai;Jiang, Nan;Yang, Yuanzhu;Liu, Xin;Fu, Jun;Deng, Zhao;Hu, Xiaochun;Tu, Zhouyi;Wang, Qiuyi;Chen, Pengcheng;Bai, Zhenan;Liu, Tiangang;Zhang, Xuanwen;Qin, Peng;Wang, Kai;Jiang, Nan;Yang, Yuanzhu;Liu, Xin;Fu, Jun;Deng, Zhao;Hu, Xiaochun;Tu, Zhouyi;Chen, Pengcheng;Bai, Zhenan;Liu, Tiangang;Zhang, Xuanwen;Qin, Peng;Wang, Kai;Jiang, Nan;Yang, Yuanzhu;Chen, Xinwei;Zhu, Yuxuan;Wang, Kai;Yang, Yuanzhu;Wang, Qiuyi;Qin, Peng;Wang, Kai;Jiang, Nan;Yang, Yuanzhu

    关键词：Magnaporthe oryzae; rice blast; SNP; genetic diversity; population structure; mating type

微信小程序