The combination of metabolome and transcriptome clarifies the inhibition of the Alternaria toxin accumulation by methyl ferulate
文献类型： 外文期刊
第一作者： Ge, Shuai
作者： Ge, Shuai;Xie, Ying;Ding, Ke;Xu, Saiqing;Xu, Haishan;Chang, Xia;Shan, Yang;Ding, Shenghu;Ge, Shuai;Xie, Ying;Ding, Ke;Xu, Saiqing;Xu, Haishan;Chang, Xia;Li, Huan;Shan, Yang;Ding, Shenghu;Wang, Rongrong;Luo, Zisheng
作者机构：
关键词： Alternaria alternata; Alternaria toxin; Methyl ferulate; Transcriptome; Metabolome
期刊名称：FOOD CHEMISTRY （ 影响因子：8.5； 五年影响因子：8.2 ）
ISSN： 0308-8146
年卷期： 2024 年 456 卷
页码：
收录情况： SCI
摘要： As one of the most typical pathogens in fruit postharvest diseases, Alternaria alternata (A. alternata) can produce Alternaria toxins (ATs) aggravating fruit decay and harming human health. In this study, ATs (tenuazonic acid, alternariol monomethyl ether, and alternariol) production was inhibited effectively by 200 and 8000 mg/L MF (methyl ferulate) in vitro and in vivo. 1-Octen-3-ol and 3-octanol were the potential iconic volatile organic compounds of ATs (R-2 > 0.99). MF induced oxidative stress, resulting in physiological and metabolic disorders, membrane lipid oxidation and cell damage. It decreased precursors and energy supply by disturbing amino acid metabolism, ABC transporters, citrate cycle, pentose and glucuronate interconversions to regulate ATs synthesis. MF down-regulated the genes related to ATs synthesis (PksJ, AaTAS1, and OmtI), transport (AaMFS1 and MFS), and pathogenicity to affect ATs production and virulence. This study provided a theoretical basis for the control of ATs production.
分类号：
- 相关文献
作者其他论文 更多>>
-
PTEN regulated by gga-miR-20a-5p is involved in chicken macrophages inflammatory response to APEC infection via autophagy
作者：Sun, Hong-yan;Ma, Yu-yi;Cao, Xin-qi;Li, Huan;Han, Wei;Qu, Lu-Jiang;Lamont, Susan J.
关键词：Avian pathogenic E. coli; PTEN; inflammatory response; autophagy; gga-miR-20a-5p
-
Untargeted Metabolomic Analyses and Antilipidemic Effects of Citrus Physiological Premature Fruit Drop
作者：Wang, Chao;Peng, Mingfang;Fu, Fuhua;Li, Gaoyang;Su, Donglin;Shan, Yang;Wang, Chao;Peng, Mingfang;Fu, Fuhua;Li, Gaoyang;Su, Donglin;Huang, Lvhong;Guo, Jiajing;Gao, Zhipeng;Han, Qi
关键词：citrus premature fruit drop; bioactive components; antioxidant; untargeted metabolomics; antilipidemic effect
-
Systems Metabolic Engineering of Saccharomyces cerevisiae for the High-Level Production of (2S)-Eriodictyol
作者：Zhang, Siqi;Liu, Juan;Xiao, Zhiqiang;Tan, Xinjia;Wang, Yongtong;Zhao, Yifei;Jiang, Ning;Shan, Yang;Zhang, Siqi;Liu, Juan;Xiao, Zhiqiang;Tan, Xinjia;Wang, Yongtong;Zhao, Yifei;Jiang, Ning;Shan, Yang;Zhang, Siqi;Liu, Juan;Xiao, Zhiqiang;Tan, Xinjia;Wang, Yongtong;Zhao, Yifei;Jiang, Ning;Shan, Yang;Liu, Juan
关键词：flavonoid; (2S)-naringenin; (2S)-eriodictyol; metabolic engineering; metabolic balance
-
Evaluation the kill rate and mutant selection window of danofloxacin against Actinobacillus pleuropneumoniae in a peristaltic pump model
作者：Wang, Hongjuan;Liao, Chengshui;Ding, Ke;Zhang, Longfei;Wang, Lei;Wang, Hongjuan;Liao, Chengshui;Ding, Ke;Wang, Lei
关键词：Actinobacillus pleuropneumoniae; Kill rate; Mutation selection window; Peristaltic pump model; PK/PD integration
-
Biochemical and Molecular Insights into Variation in Sesame Seed Antioxidant Capability as Revealed by Metabolomics and Transcriptomics Analysis
作者：Dossou, Senouwa Segla Koffi;Luo, Zishu;Deng, Qianchun;Zhou, Rong;Zhang, Yanxin;Li, Donghua;Li, Huan;You, Jun;Wang, Linhai;Dossou, Senouwa Segla Koffi;Tozo, Koffi
关键词：sesame; antioxidant; polyphenol profiling; transcriptomics; seed coat color; LC-MS
-
Nondestructive prediction of lime acidity with a single scan using two types of near infrared spectrometers and ensemble learning strategy
作者：Li, Pao;Dong, Yiqing;Jiang, Liwen;Du, Guorong;Shan, Yang;Li, Pao;Shan, Yang;Li, Pao;Du, Guorong
关键词：Nondestructive detection; Near infrared spectroscopy; Lime; Available acidity; Total acidity; Ensemble learning
-
Maintaining the balance of fungal community through active packaging film makes strawberry fruit pose pleasant flavor during storage
作者：Xu, Haishan;Quan, Qi;Chang, Xia;Ge, Shuai;Xu, Saiqing;Shan, Yang;Ding, Shenghua;Xu, Haishan;Chang, Xia;Ge, Shuai;Xu, Saiqing;Shan, Yang;Ding, Shenghua;Wang, Rongrong;Xu, Yanqun;Luo, Zisheng
关键词：Strawberry; Gelatin composite film; Flavor; Fungal community; Spearman correlation analysis
