Phytochemistry and Pharmacology of Sesquiterpenoids from Atractylodes DC. Genus Rhizomes

文献类型： 外文期刊

第一作者： Qu, Zhengyi

作者： Qu, Zhengyi;Zhao, Shuting;Hou, Wei;Qu, Zhengyi;Zhao, Shuting;Hou, Wei;Liu, Hongqun;Zhang, Zhenghai;Zheng, Peihe

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关键词： Atractylodes DC. rhizomes; sesquiterpenes; eudesmane-type; phytochemistry; biosynthetic pathways; pharmacology

期刊名称：MOLECULES （ 影响因子：4.6； 五年影响因子：4.9 ）

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年卷期： 2024 年 29 卷 6 期

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收录情况： SCI

摘要： The rhizomes of the genus Atractylodes DC. consist of various bioactive components, including sesquiterpenes, which have attracted a great deal of research interest in recent years. In the present study, we reviewed the previously published literatures prior to November 2023 on the chemical structures, biosynthetic pathways, and pharmacological activities of the sesquiterpenoids from this genus via online databases such as Web of Science, Google Scholar, and ScienceDirect. Phytochemical studies have led to the identification of more than 160 sesquiterpenes, notably eudesmane-type sesquiterpenes. Many pharmacological activities have been demonstrated, particularly anticancer, anti-inflammatory, and antibacterial and antiviral activities. This review presents updated, comprehensive and categorized information on the phytochemistry and pharmacology of sesquiterpenes in Atractylodes DC., with the aim of offering guidance for the future exploitation and utilization of active ingredients in this genus.

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