Study on an antifouling and blood compatible poly(ethylene-vinyl acetate) material with fluorinated surface structure

文献类型: 外文期刊

第一作者: Wen, Xiao-Wen

作者: Wen, Xiao-Wen;Pei, Su-Peng;Li, Hong;Ai, Fei;Chen, Huan;Zhang, Yong-Ming;Li, Ke-Yong;Wang, Quan

作者机构:

关键词: IN-VITRO;FLUOROCARBON COATINGS;PROTEIN ADSORPTION;PLATELET-ADHESION;SERUM-ALBUMIN;PLASMA;POLYMER;FILMS;DEPOSITION;CHEMISTRY

期刊名称:JOURNAL OF MATERIALS SCIENCE ( 影响因子:4.22; 五年影响因子:3.69 )

ISSN:

年卷期:

页码:

收录情况: SCI

摘要: Novel poly(ethylene-vinyl acetate) film with fluorinated surface structure was prepared via sequential surface reactions, which are alcoholysis reaction with sodium ethoxide and located fluorination reaction with 2,3,3,3-tetrafluoro-2-[1,1,2,3,3,3-hexafluoro-2-(heptafluoropropoxy)prop oxy] propionyl fluoride, respectively. The obtained novel film possesses ordered perfluoroalkyl ether surface layer proved by detailed ATR-FTIR, XPS, and contact angle measurement, which substantiates the success of this new route to get better-tailored surface meeting the biological needs. Hemocompatibility of the resultant films was evaluated by hemolysis test and platelet adhesion test. The results indicated that the poly(ethylene-vinyl acetate) film surface displayed low hemolytic activity and no platelet adhesion due to its extremely low surface tension, which results from the special micro-electric field of perfluoroalkyl ether layer. The yielded transparent film with good properties exhibits a promising application prospect in biology and medical science in view of its flexible substrate and unique biocompatible surface.

分类号: TB3

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