Transcriptome analysis of Reticulitermes flaviceps exposed to Mentha spicata essential oil and carvone indicates a potential neurotoxic mechanism of action characterized by intracellular calcium influx mediated by dopamine receptors
文献类型： 外文期刊
第一作者： Xie, Yongjian
作者： Xie, Yongjian;Chen, Yiyang;Wu, Ziwei;Yang, Shimeng;Zhang, Dayu;Gong, Xue;Zhang, Zhilin
作者机构：
关键词： Mentha spicata; Carvone; Fumigation; Reticulitermes flaviceps; Differentially expressed genes (DEGs); Neurotoxicity
期刊名称：PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY （ 影响因子：4.2； 五年影响因子：4.6 ）
ISSN： 0048-3575
年卷期： 2024 年 204 卷
页码：
收录情况： SCI
摘要： Reticulitermes flaviceps is an economically important pest in agriculture, forestry, and construction. Recent studies have shown an increase in research focusing on the anti-termite properties of plant essential oils, however, there remains a lack of information regarding the specific molecular mechanism involved. In this study, RNA-seq analysis was conducted on termites exposed to Mentha spicata essential oil (EO) and carvone, leading to the discovery of various genes that were expressed differentially under different treatment conditions. Numerous genes that exhibited a response to M. spicata EO and carvone found to be associated with stress-related pathways, such as drug metabolism cytochrome P450, glutathione metabolism, fatty acid metabolism, citric acid cycle, neuroactive ligand-receptor interaction, cell apoptosis, the AMPK signalling pathway, the mTOR signalling pathway, the longevity regulation pathway, ubiquitin-mediated protein hydrolysis, and the calcium signalling pathway. The up-regulation of genes (SPHK) associated with calcium channels, such as SPHK, indicates a potential mechanism of neurotoxicity, while the up-regulation of apoptosis-associated genes, including ACTB_G1, PYG, SQSTM1, RNF31, suggests a potential mechanism of cytotoxicity. The metabolism of M. spicata EO induces oxidative stress, elevates free Ca2+ levels in mitochondria, and initiates the generation of reactive oxygen species (ROS), ultimately resulting in programmed cell necrosis and apoptosis, as well as facilitating cellular autophagy. The monoterpenes exhibited neurotoxic and cytotoxic effects on R. flaviceps and could be exploited to advance termiticide development and eco-friendly termite control.
分类号：
- 相关文献
作者其他论文 更多>>
-
A lipoxygenase gene modulates jasmonate biosynthesis to enhance blast resistance in rice
作者：Wang, Lanlan;Deng, Fan;Gong, Xue;Wu, Gengwei;Zhang, Chi;Wang, Hua;Chen, Yumeng;Jin, Gaochen;Li, Ran;Deng, Fan
关键词：13-Lipoxygenase; jasmonic acid (JA); Magnaporthe oryzae; MYC2 transcription factor; rice; rice blast resistance
-
Integrating Random Forest With Boundary Enhancement for Mapping Crop Planting Structure at the Parcel Level From Remote Sensing Images
作者：Xie, Junyang;Li, Yan;Wu, Hao;Wu, Ziwei;Zhao, Ruina;Lin, Anqi;Xie, Junyang;Li, Yan;Wu, Hao;Wu, Ziwei;Zhao, Ruina;Lin, Anqi;Adami, Marcos;Li, Guoqiang;Zhang, Jian
关键词：Crops; Feature extraction; Remote sensing; Accuracy; Image edge detection; Random forests; Data mining; Deep learning; Normalized difference vegetation index; Cotton; Crop planting structure; deep learning; farmland parcel extraction; parcel level; random forest (RF); remote sensing
-
Ultrasoft, anti-dehydrated, and highly stretchable carboxymethylcellulose-based organohydrogel strain sensors for non-invasive real-time plant growth monitoring
作者：Wang, Lina;Li, Hai;Xu, Xinye;Zhang, Zhilin;Xu, Jingkun;Huang, Yao;Lu, Baoyang;Wang, Lina;Chen, Wenna;Xu, Xinye;Huang, Yao;Lu, Baoyang;Wu, Lidong
关键词：Strain sensor; Organohydrogel; Carboxymethylcellulose; Anti-dehydration; High stretchability; Wireless sensing system
-
The mutation in the critical sterility-inducing temperature-regulating gene OsTMS5 and OsCSIT1 enhances cadmium tolerance in rice seedlings
作者：Wang, Tao;He, Yi;Wang, Tao;He, Yi;Deng, Fan;Gong, Xue;Wu, Gengwei;Wang, Lanlan;Zhang, Chi;Wang, Hua;Shen, Renfang;Zhu, Xiaofang;Huang, Jiu;Wang, Feng
关键词：Cadmium;
OsCSIT1 ; Rice -
Variability of arabinoxylan and phytochemicals in refined and whole wheat flour: Insights for wheat quality improvement
作者：Gong, Xue;Chen, Feng;Gong, Xue;Chen, Tiantian;Tian, Yuanyuan;Zhang, Yan;He, Zhonghu;Tian, Wenfei;He, Zhonghu;Tian, Wenfei;Ibba, Maria Itria;Wang, Changhai
关键词：Arabinoxylan; Alkylresorcinols; Phenolic acid; Wheat quality improvement
-
Effects of psyllium polysaccharide with different molecular weights on the digestibility, physicochemical properties of rice starch, and interaction forces between them
作者：Gong, Xue;Li, Jiaxin;Li, Yang;Zhang, Yue;Wang, Fengzhong;Tong, Li-Tao;Liu, Zhigang;Xu, Xuebing
关键词：Psyllium polysaccharides; Molecular weight; Rice starch
-
Ferulic acid concentration in 233 maize inbreds and its processing stability in selected high-ferulic-acid lines
作者：Gong, Xue;Li, Yuan;Liu, Li;Fu, Jindong;He, Zhonghu;Li, Liang;Tian, Wenfei;Liu, Li;Fu, Jindong;He, Zhonghu;Tian, Wenfei
关键词：Maize; Ferulic acid; Functional food; Phytochemical; Whole grain
