The unconventional prefoldin RPB5 interactor mediates the gravitropic response by modulating cytoskeleton organization and auxin transport in Arabidopsis

文献类型： 外文期刊

第一作者： Yang, Yi

作者： Yang, Yi;Liu, Fang;Zhu, Mingyue;Yuan, Jinfeng;Wang, Yonghong;Li, Xugang;Wang, Yong;Yang, Yi;Yang, Yi;Zhu, Mingyue;Yuan, Jinfeng;Palme, Klaus;Li, Xugang;Liu, Fang;Liu, Le;Palme, Klaus;Mai, Yan-Xia;Wang, Long;Zou, Jun-Jie;Le, Jie;Le, Jie

作者机构：

关键词： Arabidopsis; auxin; cytoskeleton; PIN2; prefoldin (PFD); unconventional prefoldin RPB5 interactor (URI)

期刊名称：JOURNAL OF INTEGRATIVE PLANT BIOLOGY （ 影响因子：9.106； 五年影响因子：8.241 ）

ISSN： 1672-9072

年卷期： 2022 年 64 卷 10 期

页码：

收录情况： SCI

摘要： Gravity-induced root curvature involves the asymmetric distribution of the phytohormone auxin. This response depends on the concerted activities of the auxin transporters such as PIN-FORMED (PIN) proteins for auxin efflux and AUXIN RESISTANT 1 (AUX1) for auxin influx. However, how the auxin gradient is established remains elusive. Here we identified a new mutant with a short root, strong auxin distribution in the lateral root cap and an impaired gravitropic response. The causal gene encoded an Arabidopsis homolog of the human unconventional prefoldin RPB5 interactor (URI). AtURI interacted with prefoldin 2 (PFD2) and PFD6, two beta-type PFD members that modulate actin and tubulin patterning in roots. The auxin reporter DR5(rev):GFP showed that asymmetric auxin redistribution after gravistimulation is disordered in aturi-1 root tips. Treatment with the endomembrane protein trafficking inhibitor brefeldin A indicated that recycling of the auxin transporter PIN2 is disrupted in aturi-1 roots as well as in pfd mutants. We propose that AtURI cooperates with PFDs to recycle PIN2 and modulate auxin distribution.

分类号：

  • 相关文献
作者其他论文 更多>>

微信小程序