Cultivation, LD50 determination and experimental model of Streptococcus suis serotype 2 strain HA9801
文献类型： 外文期刊
第一作者： Wang, Jian
作者： Wang, Jian;Liu, Peihong;Zhang, Suhua;Zhao, Zhanzhong;Xu, Feiqun;Gong, Jianpei;Huang, Xiqin;Li, Bin
作者机构：
期刊名称：RESEARCH IN VETERINARY SCIENCE （ 影响因子：2.534； 五年影响因子：2.382 ）
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年卷期：
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收录情况： SCI
摘要： The effects of nutritional components and submerged culture conditions on colony-forming unit (CFU) counts by Streptococcus suis serotype 2 strain HA9801 in flask culture was investigated, and the optimal medium and cultivation conditions was confirmed by using a 50 l bioreactor. The LD50 values of HA9801 in pigs before and after fermentation were 1.8 x 10(7) CFU, which indicated that the virulence of HA9801 was very stable in the fermentation process. In addition, an experimental model that closely mimics naturally occurring disease in conventional pigs was established.
分类号： S85
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