Preparation and characterization of catechol-functionalized chitosan thermosensitive hydrogels

文献类型： 外文期刊

第一作者： Zhang, D. Y.

作者： Zhang, D. Y.;Hu, Z.;Lu, S. T.;Li, S. D.;Yang, Z. M.;Li, P. W.

作者机构：

期刊名称：2ND INTERNATIONAL CONFERENCE ON MATERIAL STRENGTH AND APPLIED MECHANICS

ISSN： 1757-8981

年卷期： 2019 年 629 卷

页码：

收录情况： SCI

摘要： Catechol functionalization of chitosan was modified by EDC coupling reaction and then catechol-functionalized chitosan thermosensitive hydrogels were prepared by catechol-functionalization of chitosan with beta-glycerophosphate disodium as a thermosensitizer. The hydrogels were then characterized by FTIR, H-1-NMR, SEM and rheology analysis. The results demonstrated that the thermosensitive hydrogels were prepared at 37 degrees C within several minutes by mixing 2% catechol-functionalized chitosan with 30% beta-glycerophosphate disodium at a ratio of 8:2, and these thermosensitive hydrogels with porous network structure were expected to be developed as biomedical materials with wide applications.

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