The Subunit Nto1 of the NuA3 Complex Is Associated with Conidiation, Oxidative Stress Response, and Pathogenicity in Fusarium oxysporum

文献类型: 外文期刊

第一作者: Li, Erfeng

作者: Li, Erfeng;Xiao, Jiling;Yang, Yuhong;Xie, Bingyan;Mao, Zhenchuan

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关键词: Fusarium oxysporum; Nto1; gene deletion; pathogenicity

期刊名称:HORTICULTURAE ( 影响因子:2.923; 五年影响因子:3.582 )

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年卷期: 2022 年 8 卷 6 期

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收录情况: SCI

摘要: Fusarium oxysporum f. sp. conglutinans (FOC) is the dominant pathogen of vascular wilt disease on cabbage and other crucifers. Foc-Nto1 was confirmed to be the homologous protein of Nto1, a subunit of the NuA3 (nucleosomal acetyltransferase of histone H3) complex in Saccharomyces cerevisiae. FOC contains two races, race 1 and race 2. The functions of Nto1 in both races were investigated through functional genetics analyses. The Nto1-deleted mutants were decreased in conidium production and displayed increased sensitivity to hydrogen peroxide. These mutants also had reduced virulence on cabbage. The study provided evidence that Nto1 is a potential metabolic- and pathogenic-related factor in F. oxysporum.

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