Phylogenetic analysis of two goat-origin PCV2 isolates in China

文献类型： 外文期刊

第一作者： Wang, Xiaomin

作者： Wang, Xiaomin;Li, Wenliang;Xu, Xianglan;Wang, Wei;He, Kongwang;Wang, Xiaomin;Xu, Xianglan;Fan, Hongjie;Wang, Xiaomin;He, Kongwang;Fan, Hongjie

作者机构：

关键词： PCV2; Goat; Phylogenetic analysis; Genetic diversity

期刊名称：GENE （ 影响因子：3.688； 五年影响因子：3.329 ）

ISSN： 0378-1119

年卷期： 2018 年 651 卷

页码：

收录情况： SCI

摘要： Complete genome characterization of non-porcine origin Porcine circovirus type 2 (PCV2) was first described in 2014 in China. In the present study, we first identified PCV2 nucleotides in goat samples and the prevalence of PCV2 in goat was 6.15%. However, only two new strains, Goat2014-4 and Goat2014-5, could be completely sequenced. The genome of the strain Goat2014-4, which collected from the goat infected with PPRV, contains 1766 nt; strain Goat2014-5, which originated from a healthy goat, is comprised of 1767 nt. The results showed that they shared the highest nucleotide identity with BDH and the lowest similarity with DK198OPMWSfree strain and they belonged only to genotype PCV2d. Meanwhile, they shared higher homology with porcine-origin PCV2 strains than others. Moreover, a detailed analysis of the capsid amino acid sequences revealed that there were distinct differences for goat2014-4 (708 bp) and goat2014-5 (705 bp); strain Goat2014-4 showed an elongation of two amino acids, and strains Goat 2014-5 showed an elongation of one amino acid compared with other reference strains. This is the first report of the genetic analysis of goat-origin PCV2 isolates. It also provides an additional supported evidence for cross-species transmission of PCV2.

分类号：

  • 相关文献
作者其他论文 更多>>

微信小程序