文献类型： 外文期刊
第一作者： Gong, Xiao-Qian
作者： Gong, Xiao-Qian;Ruan, Bao-Yang;Liu, Xiao-Min;Zhang, Peng;Wang, Xiu-Hui;Wang, Qi;Shan, Tong-Ling;Tong, Wu;Zhou, Yan-Jun;Li, Guo-Xin;Zheng, Hao;Tong, Guang-Zhi;Yu, Hai;Tong, Guang-Zhi;Yu, Hai
作者机构：
关键词： Swine influenza virus; PB2-627; Pathogenicity; Virulence
期刊名称：RESEARCH IN VETERINARY SCIENCE （ 影响因子：2.534； 五年影响因子：2.382 ）
ISSN： 0034-5288
年卷期： 2018 年 117 卷
页码：
收录情况： SCI
摘要： PB2-627K is an important amino acid that determines the virulence of some influenza A viruses. However, it has not been experimentally investigated in the H3N2 swine influenza virus. To explore the potential role of PB2-K627E substitution in H3N2 swine influenza virus, the growth properties and pathogenicity between H3N2 swine influenza virus and its PB2-K627E mutant were compared. For the first time, our results showed that PB2-K627E mutation attenuates H3N2 swine influenza virus in mammalian cells and in mice, suggesting that PB2-627K is required for viral replication and pathogenicity of H3N2 swine influenza virus.
分类号：
- 相关文献
作者其他论文 更多>>
-
Variation in microbial communities and network ecological clusters driven by soil organic carbon in an inshore saline soil amended with hydrochar in Yellow River Delta, China
作者：Yao, Hui;Cheng, Yadong;Kong, Qingxian;Wang, Xiao;You, Xiangwei;Li, Yiqiang;Yao, Hui;Cheng, Yadong;Wang, Xiao;You, Xiangwei;Li, Yiqiang;Rong, Ziguo;Quan, Yue;Zheng, Hao
关键词：Soil carbon; Hydrochar; Soil microorganism; Ecological cluster; Coastal salt-affected soil; Soil health
-
Japanese encephalitis virus NS3 captures the protein translation element by interacting with HNRNPH1 to promote viral replication
作者：Wang, Xingya;Li, Lin;Liu, Xuelan;Wang, Xingya;Kong, Ning;Wang, Chen;Qin, Wenzhen;Yang, Xinyu;Yu, Hai;Tong, Wu;Tong, Guangzhi;Zheng, Hao;Shan, Tongling;Kong, Ning;Yu, Hai;Tong, Wu;Tong, Guangzhi;Zheng, Hao;Shan, Tongling;Liu, Xuelan
关键词：JEV; NS3; HNRNPH1; Translation regulation element
-
Deep placement of controlled-release and common urea achieves the win-win of enhancing maize productivity and decreasing environmental pollution
作者：Wu, Peng;Yu, Jinyu;Wang, Qinhe;Liu, Zeyu;Huang, Hua;Wu, Qi;Zhang, Guangxin;Sun, Min;Gao, Zhiqiang;Xue, Jianfu;Wu, Peng;Yang, Kejun;Wu, Peng;Ren, Liangqi;Zhang, Peng;Jia, Zhikuan;Liu, Enke;Bangura, Kemoh;Xue, Jianfu
关键词：Deep fertilization; Fertilizer management strategy; Greenhouse gas; Maize productivity; NH3
-
Lactiplantibacillus plantarum BXM2 Treatment Alleviates Disorders Induced by a High-Fat Diet in Mice by Improving Intestinal Health and Modulating the Gut Microbiota
作者：Cai, Xiaohui;Sun, Meng;Zheng, Yafeng;Huang, Juqing;Guan, Xuefang;Wang, Qi;Huang, Juqing;Guan, Xuefang;Wang, Qi;Yu, Tian;Zhao, Dazhou
关键词：obesity; probiotic; gut microbiota; cytokines;
Lactiplantibacillus plantarum BXM2 -
Influence of the 'painless' TRP channel on temperature-dependent escape and humidity-related pupation in Bactrocera dorsalis larvae
作者：Zhang, Yan;Zhang, Panpan;Luo, Zhicai;Wang, Qi;Zhang, Jie;Yang, Minghuan;Yan, Shanchun;Liu, Wei;Wang, Guirong
关键词：Bactrocera dorsalis; Bdorpainless; CRISPR/Cas9; extreme environments; escape behavior
-
Natural variation in ZmNRT2.5 modulates husk leaf width and promotes seed protein content in maize
作者：Wang, Qi;Wang, Min;Wang, Jin-Yu;Tan, Wei-Ming;He, Yan;Xia, Ai-Ai;Wang, Zi;Luo, Jin-Hong;He, Yan;Xu, Tao;Jia, De-Tao;Lu, Ming
关键词：maize; GWAS; husk leaf width; seed protein content;
ZmNRT2.5 -
Phthalates esters disrupt demersal fish behavior: Unveiling the brain-gut axis impact
作者：Liu, Liuqingqing;Li, Xinyao;Luo, Xianxiang;Liu, Linjia;Yuan, Zixi;Sun, Cuizhu;Zheng, Hao;Li, Fengmin;Luo, Xianxiang;Zheng, Hao;Li, Fengmin;Wang, Xiao;Xu, Elvis Genbo
关键词：Endocrine disrupting chemicals; Neurotoxicity; Brain-gut axis; Anxiety behavior; Gut microbiome; Behavioral ecology
