Recent Progress of Novel Steroid Derivatives and Their Potential Biological Properties
文献类型: 外文期刊
第一作者: Ke, Shaoyong
作者: Ke, Shaoyong
作者机构:
关键词: Biological properties; derivatives; diversity; recent progress; steroid; structure
期刊名称:MINI-REVIEWS IN MEDICINAL CHEMISTRY ( 影响因子:3.862; 五年影响因子:3.742 )
ISSN: 1389-5575
年卷期: 2018 年 18 卷 9 期
页码:
收录情况: SCI
摘要: Steroid and its derivatives have been proved to have important and diverse biological functions, which present the wide spectrum of biological activities such as antitumor, antiviral, antibacterial, antimicrobial, antifungal, antioxidant, insecticidal, aromatase inhibitors, 5 alpha-reductase inhibitors and neuromuscular blocking agents etc. Versatile features of steroid-derived compounds have emerged, so the aim of the present paper is to review the recent advances of steroid-based derivatives mainly focused on their structures and biological applications, which can be employed for further development to discover potential drug candidates.
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