文献类型： 外文期刊
第一作者： Fu, Yuguang
作者： Fu, Yuguang;Tong, Jie;Meng, Fandan;Herrler, Georg;Fu, Yuguang;Liu, Guangliang;Yin, Xiangping;Hoeltig, Doris;Hoeltig, Doris
作者机构：
期刊名称：VETERINARY RESEARCH （ 影响因子：3.683； 五年影响因子：4.106 ）
ISSN： 0928-4249
年卷期： 2018 年 49 卷
页码：
收录情况： SCI
摘要： Porcine precision-cut lung slices (PCLS) were used to analyze the effect of the ciliary activity on infection of airway epithelial cells by influenza viruses. Treatment of slices with 2% NaCl for 30 min resulted in reversible ciliostasis. When PCLS were infected by a swine influenza virus of the H3N2 subtype under ciliostatic conditions, the viral yield was about twofold or threefold higher at 24 or 48 h post-infection, respectively, as compared to slices with ciliary activity. Therefore, the cilia beating not only transports the mucus out of the airways, it also impedes virus infection.
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