文献类型： 外文期刊

第一作者： Zhou Xiao-Mao

作者： Zhou Xiao-Mao;Wang Zan-Yong;Deng Xi-Le;Yang Xin-Ling;Rui Chang-Hui

作者机构：

关键词： synthesis; bicyclic pyrazole amide; crystal structure; insecticidal activity

期刊名称：CHINESE JOURNAL OF STRUCTURAL CHEMISTRY （ 影响因子：0.893； 五年影响因子：0.603 ）

ISSN： 0254-5861

年卷期： 2018 年 37 卷 4 期

页码：

收录情况： SCI

摘要： The title compound N-(pyridin-2-ylmcthyl)-l-phenyl-1,4,5,6,7,8-hexahydrocyclohepta[c]pyrazole-3-carboxamide 5 (C21H22N4O, M-r = 346.42) has been synthesized and structurally characterized by IR, H-1 NMR, C-13 NMR, H RMS and single-crystal X-ray diffraction. The crystal crystallizes in monoclinic system, space group P2(1)/n with a = 8.668(2), b = 22.236(4), c = 9.539(2) #x212B;,beta = 108.68(3)degrees, V= 1786.4(7) #x212B(3), Z = 4, Dx= 1.288 g/cm(-3), F(000) = 736, mu(MoKa) = 0.649 mm(-1), the final R = 0.0354 and wR = 0.0933 with 3234 observed reflections with I > 2 sigma(I). The benzene and pyrazole rings are nearly coplanar with a dihedral angle of 50.977(46)degrees. The dihedral angle between the central pyrazole and pyridine rings is 11.688(46)degrees. No classical hydrogen bonds were found in the molecules. Two adjacent molecules in crystal packing of compound 5 were linked by two intramolecular hydrogen-bonding interactions C(15)-H(15)...O(l) to generate a stable structure. Compound 5 had weak insecticidal activity against the diamondback moth (Plutella xylostella), but exhibited good activity against cotton bollworm (Helicoverpa armigera).

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