Biologically active quinoline and quinazoline alkaloids part II

文献类型: 外文期刊

第一作者: Shang, Xiao-Fei

作者: Shang, Xiao-Fei;Zhang, Ji-Yu;Shang, Xiao-Fei;Yang, Guan-Zhou;Liu, Ying-Qian;Xu, Xiao-Shan;Li, Jun-Cai;Morris-Natschke, Susan L.;Goto, Masuo;Lee, Kuo-Hsiung;Lee, Kuo-Hsiung;Guo, Xiao

作者机构:

关键词: biological activities; camptothecin; natural products; quinazoline alkaloids; quinoline alkaloids

期刊名称:MEDICINAL RESEARCH REVIEWS ( 影响因子:12.944; 五年影响因子:12.341 )

ISSN: 0198-6325

年卷期: 2018 年 38 卷 5 期

页码:

收录情况: SCI

摘要: To follow-up on our prior Part I review, this Part II review summarizes and provides updated literature on novel quinoline and quinazoline alkaloids isolated during the period of 2009-2016, together with the biological activity and the mechanisms of action of these classes of natural products. Over 200 molecules with a broad range of biological activities, including antitumor, antiparasitic and insecticidal, antibacterial and antifungal, cardioprotective, antiviral, anti-inflammatory, hepatoprotective, antioxidant, anti-asthma, antitussive, and other activities, are discussed. This survey should provide new clues or possibilities for the discovery of new and better drugs from the original naturally occurring quinoline and quinazoline alkaloids.

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