Coupling oligonucleotides possessing a poly-cytosine tag with magnetic ionic liquids for sequence-specific DNA analysis
文献类型： 外文期刊
第一作者： Peng, Xitian
作者： Peng, Xitian;Peng, Xitian;Clark, Kevin D.;Ding, Xiong;Zhu, Chenghui;Varona, Marcelino;Emaus, Miranda N.;An, Jiwoo;Anderson, Jared L.
作者机构：
期刊名称：CHEMICAL COMMUNICATIONS （ 影响因子：6.222； 五年影响因子：6.008 ）
ISSN： 1359-7345
年卷期： 2018 年 54 卷 73 期
页码：
收录情况： SCI
摘要： Oligonucleotide probes were designed with a poly-cytosine region that facilitates stable anchoring to a magnetic ionic liquid support. By tethering a recognition sequence to the poly-C tag, the resulting diblock oligonucleotides distinguished single-nucleotide variants and captured DNA targets from interfering genomic DNA and cell lysate for qPCR amplification.
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