Antioxidant and antimicrobial evaluation of carboxymethylated and hydroxamated degraded polysaccharides from Sargassum fusiforrne

文献类型： 外文期刊

第一作者： Li, Yin-Ting

作者： Li, Yin-Ting;Chen, Bing-Jie;Kong, Li-Min;Zhou, Tao;Chen, Bing-Jie;Wu, Wei-Du;Ge, Kun;Zhang, Jin-Chao;Wei, Xiao-Yi;Xie, Yuan-Yuan;Gu, Jin-Ping

作者机构：

关键词： Polysaccharide from Satgassum fustforme; Antioxidant activity; Antimicrobial activity

期刊名称：INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES （ 影响因子：6.953； 五年影响因子：6.737 ）

ISSN： 0141-8130

年卷期： 2018 年 118 卷

页码：

收录情况： SCI

摘要： In order to improve the bioactivity of the polysaccharide from Sargassum fusiforme (PSF), the degraded polysaccharide (DPSF) was modified by carboxymethylation, yielding carboxymethylated degraded polysaccharides (CDPSF), which were further modified to generate hydroxamated derivatives (HCDPSF). Both CDPSF and HCDPSF were characterized by Fourier transform infrared spectroscopy. The molecular weight of CDPSF and HCDPSF was found to be 354 kDa and 375 kDa, respectively. The in vitro antioxidant activity of CDPSF and HCDPSF was evaluated by determining the radical scavenging ability and total antioxidant activity. The results indicated that the antioxidant activity of CDPSF and HCDPSF was significantly improved when compared to those of DPSF. Antimicrobial assays indicated that both CDPSF and HCDPSF possessed a marked antimicrobial ability, while DPSF did not exhibit such effects under the same conditions. Such polysaccharide derivatives have potentials in the pharmaceutical and food industries. (C) 2018 Elsevier B.V. All rights reserved.

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