Effect of quality control on the antiproliferative activity of the extract from Portulaca oleracea L. in Aspergillus flavus

文献类型： 外文期刊

第一作者： Li, Xiu-Mei

作者： Li, Xiu-Mei;Liu, Jing;Pan, Fang-Fang;Yang, Pei-Long;Li, Xiu-Mei;Yang, Pei-Long

作者机构：

关键词： antiproliferative activity; extract; high-performance liquid chromatography; Portulaca oleracea L; similarity analysis

期刊名称：BIOMEDICAL CHROMATOGRAPHY （ 影响因子：1.902； 五年影响因子：1.809 ）

ISSN： 0269-3879

年卷期： 2018 年 32 卷 12 期

页码：

收录情况： SCI

摘要： Similarity evaluation of complicated chromatographic profiles is a potential protocol for the identification and quality control of herbal medicinal products to ensure their biological activity. In this work, a high-performance liquid chromatography method was established for controlling the batch quality of the extract from Portulaca oleracea L. Using this method, the coefficients of correlation of the similarity of 10 batches extract of P. oleracea L. were >= 0.97. The 10 batch extracts from P. oleracea L. possessed stable antiproliferative activity in Aspergillus flavus. The antiproliferative activity stability is correlated with the stability quality of the of the extract from P. oleracea L. Therefore, the present study successfully set up a sensitive and efficient method which might be used to guarantee stable biological activity of the extract from P. oleracea L.

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