Effects of polysaccharides on colonic targeting and colonic fermentation of ovalbumin-ferulic acid based emulsion

文献类型： 外文期刊

第一作者： Liu, Hesheng

作者： Liu, Hesheng;Huang, Zhenzhen;Xin, Ting;Han, Lipeng;Su, Dongxiao;Dong, Lihong;Deng, Mei;Huang, Fei;Huang, Fei

作者机构：

关键词： Rutin; Ovalbumin; Emulsion; Colonic targeting; Colonic fermentation

期刊名称：FOOD CHEMISTRY （ 影响因子：8.8； 五年影响因子：8.6 ）

ISSN： 0308-8146

年卷期： 2024 年 453 卷

页码：

收录情况： SCI

摘要： Rutin is a polyphenol with beneficial pharmacological properties. However, its bioavailability is often compromised due to low solubility and poor stability. Encapsulation technologies, such as emulsion systems, have been proven to be promising delivery vehicles for enhancing the bioavailability of bioactive compounds. Thus, this study was proposed and designed to investigate the colonic targeting and colonic fermentation characteristics of rutin-loaded ovalbumin-ferulic acid -polysaccharide (OVA -FA -PS) complex emulsions. The results indicate that OVA -FA -PS emulsion effectively inhibits the degradation of rutin active substances and facilitates its transport of rutin to the colon. The analysis revealed that the OVA-FA- kappa-carrageenan emulsion loaded with rutin exhibited superior elasticity and colon targeting properties compared to the OVA-FA-hyaluronic acid or OVA -FA -sodium alginate emulsions loaded with rutin in the composite emulsion. Additionally, it was observed that the rutin loaded within the OVA-FA- kappa-carrageenan emulsion underwent degradation and was converted to 4-hydroxybenzoic acid during colonic fermentation.

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