Extraction and antioxidant activities of polysaccharides from roots of Arctium lappa L.

文献类型： 外文期刊

第一作者： Zhang, Li

作者： Zhang, Li;Yu, Jun;Li, Ya-bo;Wang, Long;Zhou, Yong-hong;Hu, Liang

作者机构：

关键词： Arctium lappa L.; Ultrasonic-assisted extraction; Polysaccharides; Antioxidant activities

期刊名称：INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES （ 影响因子：6.953； 五年影响因子：6.737 ）

ISSN： 0141-8130

年卷期： 2019 年 123 卷

页码：

收录情况： SCI

摘要： Polysaccharides were extracted from the roots of Arctium lappa L. (ALPs) using response surface methodology with ultrasonication. A central composition design was used to optimize extraction parameters by maximizing the polysaccharide extraction yield. The modified optimal conditions were as follows: water to raw material ratio of 31 mL/g, ultrasonic power of 158 W, extraction time of 83 min, and extraction temperature of 50 C. Furthermore, fractions of ALP40-1, ALP60-1, and ALP80-1 were obtained for chemical and antioxidant activity analyses after purification. Results indicated that the three fractions had a molecular weight of 218, 178, and 60 kDa, respectively, and were composed of mannose, glucose, fructose, and galactose. ALP60-1 exhibited strong scavenging activities on 1,1-diphenyl-2-picryhydrazyl, hydroxyl, and superoxide radicals. These results demonstrate that ultrasonic-assisted extraction is a very effective method for extracting ALPs, and ALP60-1 is a potential novel natural antioxidant. However, further structure elucidation and in vivo experiments are required. (C) 2018 Elsevier B.V. All rights reserved.

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