文献类型： 外文期刊
第一作者： Wang, Haoning
作者： Wang, Haoning;Wang, Xiaolong;Wang, Haoning;Kong, Ning;Yu, Hai;Zheng, Hao;Gao, Fei;Tong, Wu;Li, Liwei;Shan, Tongling;Zhang, Wen;Yang, Shixiing;Deng, Xutao;Delwart, Eric;Shan, Tongling
作者机构：
期刊名称：ARCHIVES OF VIROLOGY （ 影响因子：2.574； 五年影响因子：2.466 ）
ISSN： 0304-8608
年卷期： 2019 年 164 卷 2 期
页码：
收录情况： SCI
摘要： The complete genome of a bear picornavirus 1 (BePV-1) in the viscera of an Asian black bear (Ursus thibetanus) from China was characterized using viral metagenomics and RT-PCR/Sanger sequencing. The genome of BePV1 is 6703 nt long, contains a type-IV IRES 5'UTR with the 8-like' motif, encodes a 2053-aa-long polyprotein showing a 3-4-4 organization pattern and two 2A genes. BePV-1 showed the highest overall genome nucleotide sequence identity of 71.7% to a picornavirus genome from an Arctic ringed seal (Phoca hispida) from Canada, classified as a member of the species Aquamavirus A, currently the only one in the genus Aquamavirus. Phylogenetic and genetic distance analyses of P1 and 3D indicated that Asian bear picornavirus (aquamavirus B) represents the second sequenced member of the genus Aquamavirus.
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