文献类型： 外文期刊
第一作者： Li Hao
作者： Li Hao;Qin Ruiying;Liu Xiaoshuang;Liao Shengxiang;Xu Rongfang;Yang Jianbo;Wei Pengcheng
作者机构：
期刊名称：RICE SCIENCE （ 影响因子：3.333； 五年影响因子：4.226 ）
ISSN： 1672-6308
年卷期： 2019 年 26 卷 2 期
页码：
收录情况： SCI
摘要： Precise base editing is highly desired in plant functional genomic research and crop molecular breeding. In this study, we constructed a rice-codon optimized adenine base editor (ABE)-nCas9 tool that induced targeted A.T to G.C point mutation of a key single nucleotide polymorphism site in an important agricultural gene. Combined with the modified single-guide RNA variant, our plant ABE tool can efficiently achieve adenine base editing in the rice genome.
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