Non-Coding RNAs in Regulating Fat Deposition in Farm Animals

文献类型: 外文期刊

第一作者: Li, Jingxuan

作者: Li, Jingxuan;Zhao, Xueyan;Wang, Yanping;Wang, Jiying;Li, Jingxuan;Zhao, Xueyan;Wang, Yanping;Wang, Jiying

作者机构:

关键词: adipogenesis; miRNA; lncRNA; circRNA; farm animals

期刊名称:ANIMALS ( 影响因子:2.7; 五年影响因子:3.2 )

ISSN: 2076-2615

年卷期: 2025 年 15 卷 6 期

页码:

收录情况: SCI

摘要: Fat deposition represents a crucial feature in the expenditure of physical energy and affects the meat quality of farm animals. It is regulated by multiple genes and regulators. Of them, non-coding RNAs (ncRNAs) play a critical role in modulating the fat deposition process. As well as being an important protein source, farm animals can be used as medical models, so many researchers worldwide have explored their mechanism of fat deposition. This article summarizes the transcription factors, regulatory genes, and signaling pathways involved in the molecular regulation process of fat deposition; outlines the progress of researching the roles of microRNAs (miRNAs), long ncRNAs (lncRNAs), and circular RNAs (circRNAs) in fat deposition in common farm animals including pigs, cattle, sheep, ducks, and chickens; and identifies scientific problems in the field that must be further investigated. It has been demonstrated that ncRNAs play a critical role in regulating the fat deposition process and have great potential in improving meat quality traits.

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