FtsEX-CwlO regulates biofilm formation by a plant-beneficial rhizobacterium Bacillus velezensis SQR9

文献类型： 外文期刊

第一作者： Li, Qing

作者： Li, Qing;Li, Zunfeng;Li, Xingxing;Xia, Liming;Zhou, Xuan;Xu, Zhihui;Shao, Jiahui;Shen, Qirong;Zhang, Ruifu;Li, Qing;Zhang, Ruifu

作者机构：

关键词： Bacillus velezensis SQR9; Biofilm; FtsEX; CwlO; spo0A; Sensor kinases

期刊名称：RESEARCH IN MICROBIOLOGY （ 影响因子：3.992； 五年影响因子：4.061 ）

ISSN： 0923-2508

年卷期： 2018 年 169 卷 3 期

页码：

收录情况： SCI

摘要： Bacillus velezensis strain SQR9 is a well-investigated rhizobacterium with an outstanding ability to colonize roots, enhance plant growth and suppress soil-borne diseases. The recognition that biofilm formation by plant-beneficial bacteria is crucial for their root colonization and function has resulted in increased interest in understanding molecular mechanisms related to biofilm formation. Here, we report that the gene ftsE, encoding the ATP-binding protein of an FtsEX ABC transporter, is required for efficient SQR9 biofilm formation. FtsEX has been reported to regulate the atolysin CwlO. We provided evidence that FtsEX-CwlO was involved in the regulation of SQR9 biofilm formation; however, this effect has little to do with CwlO autolysin activity. We propose that regulation of biofilm formation by CwlO was exerted through the spo0A pathway, since transcription of spo0A cascade genes was altered and their downstream extracellular matrix genes were downregulated in SQR9 ftsE/cwlO deletion mutants. CwlO was also shown to interact physically with KinB/KinD. CwlO may therefore interact with KinB/KinD to interfere with the spo0A pathway. This study revealed that FtsEX-CwlO plays a previously undiscovered regulatory role in biofilm formation by SQR9 that may enhance root colonization and plant-beneficial functions of SQR9 and other beneficial rhizobacteria as well. (C) 2018 Institut Pasteur. Published by Elsevier Masson SAS. All rights reserved.

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