Chemical constituents from the rhizomes of Gastrodia elata f. glauca and their potential neuroprotective effects
文献类型： 外文期刊
第一作者： Wang, Zhi-Wei
作者： Wang, Zhi-Wei;Li, Yun;Mu, Yan;Dong, Hong-Jing;Wang, Xiao;Li, Yun;Zhou, Hong-Lei;Liu, Da-Hui
作者机构：
关键词： Gastrodia elata f. glauca; Neuroprotective effects; N-6-bis(4-Hydroxybenzyl) adenosine
期刊名称：PHYTOCHEMISTRY LETTERS （ 影响因子：1.679； 五年影响因子：1.861 ）
ISSN： 1874-3900
年卷期： 2018 年 24 卷
页码：
收录情况： SCI
摘要： A phytochemical study on the rhizomes of Gastrodia elata f. glauca resulted in the isolation of three new parishin derivatives and one new adenosine derivative, together with six known compounds. Their structures were elucidated mainly by spectroscopic analysis and compared to published data. All these isolates were evaluated for their neuroprotective effects against 6-hydroxydopamine-induced cell death, and new compound 4 showed potent activity with an EC50 value of 12.0 mu M.
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