Six new dihydro-beta-agarofuran sesquiterpenes from the stems and leaves of Monimopetalum chinense and their antimicrobial activities

文献类型： 外文期刊

第一作者： Zhao, Xingzeng

作者： Zhao, Xingzeng;Xu, Shu;Yin, Min;Wang, Xiangyun;Wang, Qizhi;Shan, Yu;Chen, Yu;Liu, Fei;Feng, Xu;Zhao, Xingzeng;Xu, Shu;Yin, Min;Wang, Xiangyun;Wang, Qizhi;Shan, Yu;Chen, Yu;Liu, Fei;Feng, Xu;Guo, Shenghu

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关键词： Dihydro-beta-agarofuran sesquiterpenes; Monimopetalum chinense Rehd.; Isolation; Structural elucidation; Antimicrobial activities

期刊名称：PHYTOCHEMISTRY LETTERS （ 影响因子：1.679； 五年影响因子：1.861 ）

ISSN： 1874-3900

年卷期： 2018 年 27 卷

页码：

收录情况： SCI

摘要： Six new dihydro-beta-agarofuran sesquiterpenes (1-6) were isolated from Monimopetalum chinense Rehd., and their structures were elucidated based on spectroscopic data analyses. Absolute configurations of representative compounds (1 and 3) were also determined by using quantum mechanic CD calculations. In addition, the antimicrobial activities of 1-6 against plant-pathogenic fungi and bacteria were evaluated by in vitro growth inhibition rate assay. Among test compounds, 4 and 5 showed moderate antifungal activities against some test fungi, and 5 was very effective against Botrytis cinerea. However, no inhibitory effect on test bacteria was detected for all compounds. In general, 5 is a potential lead for developing fungicide against B. cinerea.

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