Proteomic responses induced by metal pollutions in oysters Crassostrea sikamea

文献类型： 外文期刊

第一作者： Lu Zhen

作者： Lu Zhen;Ji Chenglong;Zhao Jianmin;Wu Huifeng;Lu Zhen;Ji Chenglong;Zhao Jianmin;Wu Huifeng;Shan Xiujuan;Ji Chenglong;Wu Huifeng;Lu Zhen;Shan Xiujuan;Shan Xiujuan

作者机构： Chinese Acad Sci, Yantai Inst Coastal Zone Res YIC, Key Lab Coastal Zone Environm Proc, Yantai 264003, Peoples R China;YICCAS, Shandong Prov Key Lab Coastal Zone Environm Proc, Yantai 264003, Peoples R China;Qingdao Natl Lab Marine Sci & Technol, Funct Lab Marine Fisheries Sci & Food Prod Proc, Qingdao 266237, Shandong, Peoples R China;Univ Chinese Acad Sci, Beijing 100049, Peoples R China;Minist Agr, Key Lab Sustainable Dev Marine Fisheries, Qingdao 266071, Shandong, Peoples R China;Chinese Acad Fishery Sci, Yellow Sea Fisheries Res Inst, Shandong Prov Key Lab Fishery Resources & Ecol En, Qingdao 266071, Shandong, Peoples R China

关键词： metal pollution; Crassostrea sikamea; biological effect; proteomics

期刊名称：JOURNAL OF OCEANOLOGY AND LIMNOLOGY （ 2020影响因子：1.265； 五年影响因子：1.276 ）

ISSN： 2096-5508

年卷期： 2019 年 37 卷 2 期

页码：

收录情况： SCI

摘要： There exist severe metal pollutions along the Jiulongjiang estuary in South China. In order to unravel the biological effects caused by metal pollutions, proteomic responses were investigated by two-dimensional electrophoresis-based proteomics in oysters Crassostrea sikamea from metal pollution sites, Jinshan (JS) and Baijiao (BJ), and a relatively clean site, Jiuzhen (JZ), along the Jiulongjiang estuary. Results indicated that metal pollutions mainly induced cellular injuries, oxidative and immune stresses, and disturbed ion homeostasis in oysters C. sikamea from both JS and BJ sites via differential pathways. Furthermore, metal pollution enhanced transcriptional initiation in oysters from JS site. In addition, the Cu and Fe pollution might be indicated by the 78 kDa glucose regulated protein and ferritin GF1 in oysters C. sikamea, respectively. The study confirms that proteomics is a promising approach to characterize the underlying mechanisms of responses to metal pollution in oysters.

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