Chemical study of the strain Cordyceps spp. from cell fusion between Cordyceps militaris and Cordyceps cicadae

文献类型： 外文期刊

第一作者： Ma, Qing-Yun

作者： Ma, Qing-Yun;Kong, Fan-Dong;Xie, Qing-Yi;Zhou, Li-Man;Zhao, You-Xing;Jiang, Ning;Yang, Ning-Ning;Yu, Zhi-Fang

作者机构：

关键词： Clavicipitaceae; Cordyceps spp; lactone; cyclic dipeptide; AChE inhibitory activity; anti-nematode activity

期刊名称：JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH （ 影响因子：1.569； 五年影响因子：1.598 ）

ISSN： 1028-6020

年卷期： 2019 年 21 卷 5 期

页码：

收录情况： SCI

摘要： Chemical investigation on the cultures of the fungus Cordyceps spp., a strain from cell fusion between Cordyceps militaris and Cordyceps cicadae, resulted in the isolation of 13 compounds including 2 new ones named 2-(5-(3-oxobutyl) furan-2-yl) acetic acid (1) and cordycepone (2). Their structures were elucidated from the analysis of 1D/2D NMR and CD data. Among them, compounds 1, 7-9, at a concentration of 50 mu g/ml, showed weak inhibitory activity against AChE. Moreover, compounds 6, 9, and 11 showed moderate inhibitory activity against the nematode Panagrellus redivivus with mortality ratio of 79.0, 71.7, and 72.3% at 2.5 mg/ml, respectively. [GRAPHICS] .

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