Identification of new interferences leached from plastic microcentrifuge tubes in electrospray ionization mass spectrometry

文献类型： 外文期刊

第一作者： Chai, Yunfeng

作者： Chai, Yunfeng;Chen, Hongping;Gao, Guanwei;Liu, Xin;Lu, Chengyin;Chai, Yunfeng;Chen, Hongping;Gao, Guanwei;Liu, Xin;Lu, Chengyin;Chai, Yunfeng;Chen, Hongping;Gao, Guanwei;Liu, Xin;Lu, Chengyin

作者机构：

期刊名称：RAPID COMMUNICATIONS IN MASS SPECTROMETRY （ 影响因子：2.419； 五年影响因子：2.439 ）

ISSN： 0951-4198

年卷期： 2019 年 33 卷 10 期

页码：

收录情况： SCI

摘要： Rationale The incredible sensitivity of the modern mass spectrometry instrument enables scientists to detect a large number of molecules ranging from small organic compounds to biological macromolecules. However, the same sensitivity often throws up challenges with respect to background interferences and contaminants. The identification and source of these contaminants is very important for reducing background contamination and ensuring the accuracy of the analysis results. Methods The interfering compounds were analyzed by high-performance liquid chromatography coupled with a hybrid quadrupole-orbitrap mass spectrometer. The structural analysis was conducted by obtaining the accurate masses of precursors and their fragment ions. The retention time and MS/MS spectrum of one of the interfering compounds (N-lauryldiethanolamine) were compared with an authentic standard to reach an unequivocal structural assignment. Results The interferences (m/z 274 and 318 in positive mode) were observed during the analysis of herbicides in tea samples by electrospray ionization mass spectrometry (ESI-MS). Their structures were identified to be N-lauryldiethanolamine and N-(2-hydroxyethyl)-N-(2-(2-hydroxyethoxy)ethyl)dodecylamine by fragmentation interpretation and further confirmed by a standard compound. These interferences were found to be leached from the plastic microcentrifuge tubes used during sample pretreatment. The plastic tubes from two of the five suppliers tested were found to contain these two interferences. Conclusions In this work, we presented an example about the observation, identification and source of interferences in ESI-MS. The N-lauryldiethanolamine and other ethoxylated aliphatic alkylamines are common plastic antistatic agents. They possess high proton affinity so that they show a strong response in ESI positive mode. In order to avoid their interference during mass spectrometric analysis we need to choose plastic tubes (or other plastic materials) that do not contain such antistatic agents.

分类号：

  • 相关文献
作者其他论文 更多>>
  • Metabolomics and ionomics reveal the quality differences among peach, acacia and karaya gums

    作者：Zhang, Kaiwei;Yu, Xiangyang;Zhang, Kaiwei;Chen, Meng;Zhang, Xue;Chen, Jian;Chen, Xiaolong;Li, Yong;Yu, Xiangyang;Zhang, Kaiwei;Chen, Meng;Zhang, Xue;Chen, Jian;Chen, Xiaolong;Li, Yong;Yu, Xiangyang;Liu, Xin

    关键词：Gum; Metabolomics; Flavonoids; Total phenols content; Metabolites

  • Ustiloxin A impairs oocyte quality by disrupting organelles function

    作者：Han, Jun;Wang, Gang;Liu, Xin;Zhou, You;Hu, Junqiang;Shi, Jianrong;Xu, Jianhong;Wu, Yuzhuo;Shi, Jianrong;Xu, Jianhong;Wang, Weikang

    关键词：UA; Oocyte maturation; Mitochondria; Oxidative stress; Autophagy

  • Single-cell transcriptome atlas of lamprey exploring Natterin- induced white adipose tissue browning

    作者：Pang, Yue;Du, Zeyu;Zhang, Jin;Lu, Jiali;Li, Jun;Dong, Xinrui;Zhao, Zhisheng;Chuan, Shunqin;Sun, Mingjie;Li, Qingwei;Pang, Yue;Du, Zeyu;Zhang, Jin;Lu, Jiali;Li, Jun;Dong, Xinrui;Zhao, Zhisheng;Chuan, Shunqin;Sun, Mingjie;Li, Qingwei;Qin, Yating;Liu, Qun;Han, Kai;Yuan, Zengbao;Pan, Shanshan;Xu, Mengyang;Wang, Dantong;Li, Zhen;Chen, Yadong;Song, Yue;Zhan, Liping;Cui, Wei;Wang, Jun;Fan, Guangyi;Qin, Yating;Liu, Qun;Han, Kai;Fan, Guangyi;Qin, Yating;Liu, Qun;Han, Kai;Song, Yue;Qin, Yating;Fan, Guangyi;Yuan, Zengbao;Xu, Mengyang;Wang, Dantong;Gu, Ying;Yang, Huanming;Xu, Xun;Liu, Xin;Fan, Guangyi;Xu, Mengyang;Fan, Guangyi;Li, Shuo;Zhang, Zhe;Ni, Ming;Jia, Xiaodong;Xia, Zhangyong;Yue, Zhen;Fan, Guangyi;Gu, Ying;Yang, Huanming;Xu, Xun;Liu, Xin

    关键词：

  • PbMADS49 Regulates Lignification During Stone Cell Development in 'Dangshansuli' (Pyrus bretschneideri) Fruit

    作者：Meng, Dandan;Liu, Xin;Cai, Yongping;Meng, Dandan;Duan, Jinsheng;Meng, Dandan;Duan, Jinsheng;Cao, Yunpeng

    关键词：pear; stone cell development; lignin biosynthesis; PbMADS49; PbPRX33

  • Molecular mechanism of potently neutralizing human monoclonal antibodies against severe fever with thrombocytopenia virus infection

    作者：Quan, Chuansong;Nie, Kaixiao;Zheng, Wenjun;Wang, Yiwen;Quan, Chuansong;Zhang, Hong;Quan, Chuansong;Ma, Dezhen;Su, Chao;Li, Lianfeng;Peng, Dingkun;Yin, Chunhong;Yang, Peipei;Shan, Chao;Liu, Xin;Zheng, Jie;Shi, Weifeng;Li, Weiwei;Gao, George F.;Qi, Jianxun;Liu, Weixiao;Liu, Di;Carr, Michael J.;Carr, Michael J.;Shi, Weifeng

    关键词：severe fever with thrombocytopenia syndrome; SFTSV; Bandavirus dabieense; monoclonal antibodies; neutralization; therapeutics

  • A Novel Approach for Maize Straw Type Recognition Based on UAV Imagery Integrating Height, Shape, and Spectral Information

    作者：Liu, Xin;Gong, Huili;Guo, Lin;Zhou, Jingping;Gong, Huili;Guo, Lin;Gong, Huili;Guo, Lin;Gong, Huili;Guo, Lin;Gong, Huili;Guo, Lin;Gu, Xiaohe;Zhou, Jingping

    关键词：maize straw type; multispectral imagery; SESI; object-oriented classification; UAV

  • Host-Adaptive Divergence Shapes the Genetic Architecture of Magnaporthe oryzae in Southern China's Rice Agroecosystems

    作者：Liu, Xin;Fu, Jun;Deng, Zhao;Chen, Xinwei;Hu, Xiaochun;Tu, Zhouyi;Wang, Qiuyi;Zhu, Yuxuan;Chen, Pengcheng;Bai, Zhenan;Liu, Tiangang;Zhang, Xuanwen;Qin, Peng;Wang, Kai;Jiang, Nan;Yang, Yuanzhu;Liu, Xin;Fu, Jun;Deng, Zhao;Chen, Xinwei;Hu, Xiaochun;Tu, Zhouyi;Wang, Qiuyi;Zhu, Yuxuan;Chen, Pengcheng;Bai, Zhenan;Liu, Tiangang;Zhang, Xuanwen;Qin, Peng;Wang, Kai;Jiang, Nan;Yang, Yuanzhu;Liu, Xin;Fu, Jun;Deng, Zhao;Hu, Xiaochun;Tu, Zhouyi;Wang, Qiuyi;Chen, Pengcheng;Bai, Zhenan;Liu, Tiangang;Zhang, Xuanwen;Qin, Peng;Wang, Kai;Jiang, Nan;Yang, Yuanzhu;Liu, Xin;Fu, Jun;Deng, Zhao;Hu, Xiaochun;Tu, Zhouyi;Chen, Pengcheng;Bai, Zhenan;Liu, Tiangang;Zhang, Xuanwen;Qin, Peng;Wang, Kai;Jiang, Nan;Yang, Yuanzhu;Chen, Xinwei;Zhu, Yuxuan;Wang, Kai;Yang, Yuanzhu;Wang, Qiuyi;Qin, Peng;Wang, Kai;Jiang, Nan;Yang, Yuanzhu

    关键词：Magnaporthe oryzae; rice blast; SNP; genetic diversity; population structure; mating type

微信小程序