Four new phenolic constituents from the rhizomes of Gastrodia elata Blume
文献类型: 外文期刊
第一作者: Wang, Zhi-Wei
作者: Wang, Zhi-Wei;Li, Yun;Mu, Yan;Dong, Hong-Jing;Guo, Lan-Ping;Wang, Xiao;Li, Yun;Zhou, Hong-Lei;Liu, Da-Hui
作者机构:
关键词: Phenolics; Gastrodia elata Blume; neuroprotective effects; N-6-(4-hydroxybenzyl) adenosine; grossamide
期刊名称:NATURAL PRODUCT RESEARCH ( 影响因子:2.861; 五年影响因子:2.572 )
ISSN: 1478-6419
年卷期: 2019 年 33 卷 8 期
页码:
收录情况: SCI
摘要: Four new gastrodin derivatives containing a trans-cinnamoyl unit (1-4) and nine known compounds (5-13) were isolated from the rhizomes of Gastrodia elata Blume. All these compounds were evaluated for their neuroprotective effects against 6-hydroxydopamine-induced cell death, and compounds 7 and 12 showed potent activities with EC50 values of 10.5 and 10.2 mu M, respectively. [GRAPHICS] .
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