Structural Characterization and Anti-Inflammatory Activity of Polysaccharides from Tremella fuciformis on Monosodium Urate-Stimulated RAW264.7 Macrophages
文献类型： 外文期刊
第一作者： Deng, Wei
作者： Deng, Wei;Zheng, Zhipeng;Wu, Li;Xiao, Zheng;Li, Yibin;Chen, Shouhui;Wu, Li;Xiao, Zheng;Li, Yibin;Chen, Shouhui;Wu, Li;Xiao, Zheng;Li, Yibin;Chen, Shouhui;Wu, Li;Xiao, Zheng;Li, Yibin;Chen, Shouhui
作者机构：
关键词： Tremella fuciformis; polysaccharides; transcriptomics; hypoxia inducible factor-1 signaling pathway; anti-inflammatory activity
期刊名称：FOODS （ 影响因子：5.2； 五年影响因子：5.5 ）
ISSN：
年卷期： 2023 年 12 卷 24 期
页码：
收录情况： SCI
摘要： The structural characteristics and anti-inflammatory activity of Tremella fuciformis polysaccharides (TFPs) were investigated. The study showed that TFPs were mainly composed of mannose, rhamnose, glucuronic acid, glucose, galactose, xylose, and fucose. TFPs significantly inhibited monosodium urate (MSU)-induced inflammation of RAW264.7 cells, as well as the secretion levels of TNF-alpha, IL-1 beta, and IL-18 cytokines. The concentrations of malondialdehyde and reactive oxygen species in RAW264.7 macrophages were reduced, but superoxide dismutase activity was increased. RNA-Seq technology was applied to explore the mechanisms of TFPs ameliorating MSU-induced inflammation of RAW264.7 macrophages. Results revealed that TFPs significantly reduce MSU-stimulated inflammatory damage in RAW 264.7 cells by inhibiting signaling pathways like the hypoxia inducible factor-1 (HIF-1) signaling pathway and erythroblastic oncogene B (ErbB) signaling pathway. This study provides a foundation for TFPs to be developed as novel anti-inflammatory drugs.
分类号：
- 相关文献
作者其他论文 更多>>
-
Temporal-Spatial Variations in Physicochemical Factors and Assessing Water Quality Condition in River-Lake System of Chaohu Lake Basin, China
作者：Wu, Li;Wang, Ziqi;Yang, Yujie;Sang, Rui;Zhu, Haoyue;Wang, Xitong;Pang, Yuqing;Tong, Jiangshan;Liu, Xiangting;Ma, Mingyue;Wang, Qianqian;Ma, Kaijun;Liu, Fan;Liu, Kai;Liu, Kai
关键词：water quality index; trophic level index; Chaohu Lake; spatiotemporal water quality pattern
-
Biocontrol activity and antifungal mechanisms of volatile organic compounds produced by Trichoderma asperellum XY101 against pear Valsa canker
作者：Zhang, Yang;Tang, Jian-Hong;He, Yujian;Zhang, Yang;Wu, Li;Lu, Ying;Li, Bo;Jin, Zhaoyang;Wang, Jun;Bai, Ruxiao;Wu, Qifeng;Fan, Qinglu;Yin, Feihu;He, Yujian;Wang, Jun;Bai, Ruxiao;Wu, Qifeng;Fan, Qinglu;Yin, Feihu;He, Yujian;Wang, Jun;Bai, Ruxiao;Wu, Qifeng;Fan, Qinglu;Yin, Feihu;He, Yujian
关键词：
Valsa pyri ;Trichoderma asperellum ; volatile organic compounds; antifungal activity; transcriptomics -
The SlGRAS9-SlMYC1 regulatory module controls glandular trichome formation and modulates resilience to pest in tomato
作者：Shi, Yuan;Wang, Yan;Pan, Yaowen;Deng, Changhao;Zeng, Ting;Su, Deding;Lu, Wang;Lin, Yuxiang;Han, Junnan;Deng, Wei;Li, Zhengguo;Huang, Baowen;Shi, Yuan;Wang, Yan;Pan, Yaowen;Deng, Changhao;Zeng, Ting;Su, Deding;Lu, Wang;Lin, Yuxiang;Han, Junnan;Deng, Wei;Bouzayen, Mondher;Li, Zhengguo;Huang, Baowen;Wu, Shuang;Liu, Yudong;Li, Ning;Li, Ji;Dong, Biao;Abid, Ghassen;Bouzayen, Mondher;Pirrello, Julien
关键词：trichome formation; tomato; type VI glandular trichome; terpenoid accumulation; spider mites; aphids
-
Lacticaseibacillus rhamnosus Fermentation Ameliorates Physicochemical Properties, Physiological Activity, and Volatile and Non-Volatile Compounds of Mango Juice: Preliminary Results at Laboratory Scale
作者：Fan, Jinlin;Deng, Jiacong;Guo, Weiling;Xiao, Zheng;Shi, Feifei
关键词：fruit juice;
Lactobacillus ; physicochemical properties; antioxidant; metabolomics -
The impact of nitrogen forms on the ecological function and community assembly of biocrusts in Gurbantunggut Desert
作者：Qian, Long;Liu, Xiaoyan;Gong, Yan;Qian, Long;Wang, Shiqi;Xia, Ling;Song, Shaoxian;Wu, Li;Xiao, Jingshang;Wu, Li
关键词：Biocrusts; Nitrogen; Community assembly; Ecological function; Stability
-
Isolation and Characterization of Beauveria caledonica (Ascomycota: Hypocreales) Strains for Biological Control of Odoiporus longicollis Oliver (Coleoptera: Curculionidae)
作者：Ding, Mingbi;Wu, Li;Yu, Hongwei;Fan, Huacai;Guo, Zhixiang;Xu, Shengtao;Wang, Yongfen;Zheng, Si-Jun;Ding, Mingbi;Wu, Li;Yu, Hongwei;Chun, Jianhui;Wang, Yongfen;Zheng, Si-Jun
关键词：
O. longicollis (Oliver);B. caledonica ; biological characteristics; virulence; greenhouse evaluation -
Overexpression of SlIMP3 regulates sugar metabolism, antioxidant activity, and fruit softening, leading to extended shelf life of tomato fruits
作者：Yang, Qiqi;Han, Jiarui;Xie, Qiaoli;Yang, Qiqi;Han, Jiarui;Xie, Qiaoli;Zheng, Xianzhe;Zheng, Xianzhe;Fang, Xu;Zhang, Qiongdan;Deng, Jie;Deng, Wei;Zheng, Xianzhe;Fang, Xu;Zhang, Qiongdan;Deng, Jie;Deng, Wei;Xu, Chan
关键词：Tomato; SlIMP3; Transcriptome; Metabolome; Fruit softening
