文献类型： 外文期刊
第一作者： Wang, C.
作者： Wang, C.;Yang, Y.;Liu, Y.;Li, G.;Wang, X.;Wang, H.;Gong, S.;He, D.;Zhang, Y.;Chen, S.;Song, J.;Lin, Z.
作者机构： Shanghai Acad Agr Sci, Inst Anim Husb & Vet Sci, 2901 Beidi Rd, Shanghai 201106, Peoples R China;Shanghai Ocean Univ, Coll Fisheries & Life Sci, Shanghai, Peoples R China;NingBo Acad Agr Sci, Ningbo, Peoples R China;Xiangshan Anim Husb & Vet Gen Stn, Ningbo, Peoples R China;Shantou Baisha Res Inst Original Species Poultry, Shantou, Peoples R China
关键词： Geese; IGF2BP1 gene expression; correlation; body weight
期刊名称：BRITISH POULTRY SCIENCE （ 2021影响因子：1.892； 五年影响因子：2.429 ）
ISSN： 0007-1668
收录情况： SCI
摘要： 1. The gene IGF2BP1 has been reported as being related to the body size and body weight in ducks, goats and chickens. However, this potential growth-related gene has not yet been reported in geese. 2. The goose IGF2BP1 cDNA (IGF2BP1-X1) is 2,925 bp in length, containing an open reading frame (ORF) of 1,731 bp that encodes a protein of 576 amino acids. Six IGF2BP1 transcripts (IGF2BP1-X2 similar to IGF2BP1-X7) were identified due to the alternative splicing of different exons within the IGF2BP1-X1 transcript. 3. RT-qPCR analysis indicated that the goose IGF28P1 mRNA was differentially expressed in the examined tissues of female embryos (28 d of development), adult (70 d of age) and laying (270 d of age) Zhedong White geese. 4. 4. In total, 16 single nucleotide polymorphisms (SNPs) and three insertion/deletion (InDel) variants were detected in several introns and 3'-untranslated regions of the goose IGF2BP1 gene. The 17-bp InDel within IGF2BP1 intron 14 was significantly associated with body weight at six weeks old (BW6, P < 0.05), and extremely significantly associated with the BW8 and BW10 (P < 0.01) of Zhedong White geese.
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