Estimates of Genomic Heritability and the Marker-Derived Gene for Re(Production) Traits in Xinggao Sheep

文献类型： 外文期刊

第一作者： Liu, Zaixia

作者： Liu, Zaixia;Shi, Caixia;Dai, Lingli;Chai, Yuan;Zhang, Wenguang;Liu, Zaixia;Dai, Lingli;Zhang, Wenguang;Fu, Shaoyin;Wang, Biao;Liu, Xuewen;Dai, Lingli;Liu, Yongbin

作者机构：

关键词： Xinggao sheep; LS; BWT; WWT; ADG; genetic parameter evaluation; MATs

期刊名称：GENES （ 影响因子：3.5； 五年影响因子：3.9 ）

ISSN：

年卷期： 2023 年 14 卷 3 期

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收录情况： SCI

摘要： Xinggao sheep are a breed of Chinese domestic sheep that are adapted to the extremely cold climatic features of the Hinggan League in China. The economically vital reproductive trait of ewes (litter size, LS) and productive traits of lambs (birth weight, BWT; weaning weight, WWT; and average daily gain, ADG) are expressed in females and later in life after most of the selection decisions have been made. This study estimated the genetic parameters for four traits to explore the genetic mechanisms underlying the variation, and we performed genome-wide association study (GWAS) tests on a small sample size to identify novel marker trait associations (MTAs) associated with prolificacy and growth. We detected two suggestive significant single-nucleotide polymorphisms (SNPs) associated with LS and eight significant SNPs for BWT, WWT, and ADG. These candidate loci and genes also provide valuable information for further fine-mapping of QTLs and improvement of reproductive and productive traits in sheep.

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