Physicochemical, rheological properties and in vitro hypoglycemic activities of polysaccharide fractions from peach gum

文献类型： 外文期刊

第一作者： Chen, Jiaxin

作者： Chen, Jiaxin;Zhou, Mo;Liu, Meng;Bi, Jinfeng;Chen, Jiaxin

作者机构：

关键词： Peach gum; Fractionation; Polysaccharide; a-Glucosidase; Inhibition mechanism

期刊名称：CARBOHYDRATE POLYMERS （ 影响因子：10.723； 五年影响因子：9.964 ）

ISSN： 0144-8617

年卷期： 2022 年 296 卷

页码：

收录情况： SCI

摘要： In this study, peach gum was sequentially extracted by water at 25 C, 95 C and 0.1 M NaOH, obtaining room temperature water-soluble (PG-WE), hot water-soluble (PG-HWE), and alkali-soluble (PG-AE) polysaccharide fractions. These three kinds of polysaccharide fractions exhibited a similar arabinogalactan structure according to FTIR spectrum and monosaccharide composition. However, their molecular weight and chain conformation were different based on high-performance size exclusion chromatography analysis, which resulted in different rheological behavior. PG-WE and PG-HWE presented non-Newtonian behavior, and the apparent viscosity of PG -WE was higher than that of PG-HWE at concentrations of 2.0 % and 3.0 % (w/w). Dynamic sweep tests showed that PG-HWE solutions behaved as viscous fluids, while PG-WE solutions tended to form gel-like structures at concentrations higher than 2 % (w/w). Furthermore, PG-WE showed significant in vitro inhibition against alpha-glucosidase activity in a dose-dependent manner and reduced the fluorescence of alpha-glucosidase through dy-namic quenching mechanism.

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