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Analytical methods for assessing antimicrobial activity of nanomaterials in complex media: advances, challenges, and perspectives

文献类型：外文期刊

第一作者： Zhang, Xuzhi

作者： Zhang, Xuzhi;Ma, Liangyu;Qu, Keming;Hou, Xiangyi;Hou, Xiangyi;Shi, Yaqi;Zhang, Dahai

作者机构：

关键词： Nanomaterials; Antimicrobial activity; Complex matrices; Assessment; Analytical methods

期刊名称：JOURNAL OF NANOBIOTECHNOLOGY （影响因子：10.2；五年影响因子：11.5 ）

ISSN：

年卷期： 2023 年 21 卷 1 期

页码：

收录情况： SCI

摘要： Assessing the antimicrobial activity of engineered nanomaterials (ENMs), especially in realistic scenarios, is of great significance for both basic research and applications. Multiple analytical methods are available for analysis via off-line or on-line measurements. Real-world samples are often complex with inorganic and organic components, which complicates the measurements of microbial viability and/or metabolic activity. This article highlights the recent advances achieved in analytical methods including typical applications and specifics regarding their accuracy, cost, efficiency, and user-friendliness. Methodological drawbacks, technique gaps, and future perspectives are also discussed. This review aims to help researchers select suitable methods for gaining insight into antimicrobial activities of targeted ENMs in artificial and natural complex matrices.

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