An electrochemical aptamer sensor based on AuNPs/ErGO/Cu-MOF nanocomposites for the detection of oxytetracycline in foodstuff
文献类型： 外文期刊
第一作者： Guan, Fukai
作者： Guan, Fukai;Dong, Yanjie;Wang, Lei;Cai, Da;Zhao, Shancang;Guan, Fukai;Guo, Yemin;Sheng, Qingkai
作者机构：
关键词： Aptasensor; Cu-MOF; Gold nanoparticles; Electrochemically reduced graphene oxide; Oxytetracycline
期刊名称：MICROCHEMICAL JOURNAL （ 影响因子：5.1； 五年影响因子：4.7 ）
ISSN： 0026-265X
年卷期： 2025 年 208 卷
页码：
收录情况： SCI
摘要： An aptamer sensor for the rapid and sensitive recognition of oxytetracycline (OTC) was developed by modifying a screen-printed carbon electrode with Cu-based metal organic framework (MOF), electrochemically reduced graphene oxide (ErGO), and gold nanoparticles (AuNPs). The Cu-MOF had a large surface area and accommodated AuNPs and ErGO. The electrodeposition of AuNPs and the immobilization of ErGO improved the conductivity to amplify the sensor response. The developed sensor had an extremely broad linear range (0.1-105 ng/ mL) and a very low limit of detection (0.03 ng/mL), and it was highly stable, specific, and reproducible. When used to detect OTC in milk and pork samples, the recovery ranged from 87.0 % to 110.2 %.
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