Tobacco Mosaic Virus (TMV) Inhibitors from Picrasma quassioides Benn

文献类型： 外文期刊

第一作者： Chen, Jia

作者： Chen, Jia;Yan, Xiao-Hui;Fang, Xin;Di, Ying-Tong;Hao, Xiao-Jiang;Chen, Jia;Yan, Xiao-Hui;Dong, Jia-Hong;Sang, Peng;Zhang, Zhong-Kai;Dong, Jia-Hong;Sang, Peng;Zhang, Zhong-Kai

作者机构：

关键词： Tobacco mosaic virus (TMV);Picrasma quassioides Benn.;β-carbollne;synergistic effects

期刊名称：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY （ 影响因子：5.279； 五年影响因子：5.269 ）

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收录情况： SCI

摘要： To investigate natural inhibitors against tobacco mosaic virus (TMV) from plants, 10 known β-carbolirie alkaloids and one quassinoid have been isolated from MeOH extract of the wood of Picrasma quassioides Benn. These compounds were screened for their inhibitory activities against tobacco mosaic virus (TMV). The activity of each compound against TMV infection and replication was tested using a half-leaf assay method, a leaf-disk method, and Western blotting analyses. All of the β-carboline alkaloids showed moderate anti-TMV activities and exhibited synergistic effects when combined with the quassinoid nigakilactone B (11). To our knowledge, this is the first report on anti-TMV activity of β-carbolines and their synergistic effects against TMV when combined with a quassinoid.

分类号： TQ

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