Efficacy of DNA Immunization with F and G Protein Genes of Nipah Virus

文献类型： 外文期刊

第一作者： Wang, Xijun

作者： Wang, Xijun;Ge, Jinying;Hu, Sen;Wang, Qinghua;Wen, Zhiyun;Chen, Hualan;Bu, Zhigao

作者机构：

关键词： Nipah virus;DNA immunization;F protein;G protein

期刊名称：IMPACT OF EMERGING ZOONOTIC DISEASES ON ANIMAL HEALTH

ISSN：

年卷期：

页码：

收录情况： SCI

摘要： We investigated the antibody response of DNA immunization with two mammalian codon optimized envelope glycoprotein genes, F and G, of Nipah virus in a mouse model. The results indicated that G gene immunization elicited more significant specific serum IgG response and neutralization antibody response than F gene did, suggesting that the G gene DNA immunization is a potential vaccine strategy against Nipah virus.

分类号： N

  • 相关文献

[1]Evaluation of the enhancing ability of three adjuvants for DNA vaccination using the porcine circovirus type 2 ORF2 (capsid) gene in mice. Fu, Fang,Lang, Yuekun,Li, Xuesong,Chai, Zheng,Liu, Siguo,Tian, Huabin,Li, Haizhong,Wang, Wei,Chen, Xin,Li, Xi,Li, Xuesong,Tong, Guangzhi.

[2]Co-expression of Ubiquitin gene and capsid protein gene enhances the potency of DNA immunization of PCV2 in mice. Fu, Fang,Li, Xuesong,Lang, Yuekun,Li, Xi,Li, Xuesong,Yang, Yuju,Tong, Guangzhi,Li, Guoxin,Zhou, Yanjun,Li, Xi. 2011

[3]DNA immunization elicits high HI antibody and protects chicken from AIV challenge. Chen, H,Yu, K,Jiang, Y,Tang, X. 2001

[4]An inactivated recombinant rabies CVS-11 virus expressing two copies of the glycoprotein elicits a higher level of neutralizing antibodies and provides better protection in mice. Xue, Xiang-Hong,Li, Ling,Yang, Song-Tao,Xia, Xian-Zhu,Xue, Xiang-Hong,Zheng, Xue-Xing,Wang, Hua-Lei,Ma, Jin-Zhu,Li, Ling,Gai, Wei-Wei,Wang, Tie-Cheng,Yang, Song-Tao,Xia, Xian-Zhu,Zheng, Xue-Xing,Ma, Jin-Zhu.

[5]Engineering, expression, and immuno-characterization of recombinant protein comprising multi-neutralization sites of rabies virus glycoprotein. Li, Xiangdong,Luo, Jinyan,Shen, Yang,Qiu, Yafeng,Wang, Xiaodu,Deng, Xufang,Ding, Chan,Ma, Zhiyong,Wang, Shuiming,Liu, Xuehui,Bao, Weidong,Liu, Peihong,Zhou, Jinping.

[6]A dwarfing mutant caused by deactivation function of alpha subunit of the heterotrimeric G-protein in rice. Yang, De-wei,Zheng, Xiang-hua,Cheng, Chao-ping,Lu, Li-bin,Liu, Chen-de,Ye, Ning,Zeng, Mei-juan,Ye, Xin-fu,Wang, Wen-da,Xing, Deng-hui.

作者其他论文 更多>>

微信小程序