Whole genome sequences of 70 indigenous Ethiopian cattle

文献类型： 外文期刊

第一作者： Ayalew, Wondossen

作者： Ayalew, Wondossen;Xiaoyun, Wu;Chu, Min;Liang, Chunnian;Ping, Yan;Ayalew, Wondossen;Tarekegn, Getinet Mekuriaw;Tessema, Tesfaye Sisay;Tarekegn, Getinet Mekuriaw;Enquahone, Solomon;Naboulsi, Rakan;Van Damme, Renaud;Bongcam-Rudloff, Erik;Edea, Zewdu

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期刊名称：SCIENTIFIC DATA （ 影响因子：6.9； 五年影响因子：8.7 ）

ISSN：

年卷期： 2024 年 11 卷 1 期

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收录情况： SCI

摘要： Indigenous animal genetic resources play a crucial role in preserving global genetic diversity and supporting the livelihoods of millions of people. In Ethiopia, the majority of the cattle population consists of indigenous breeds. Understanding the genetic architecture of these cattle breeds is essential for effective management and conservation efforts. In this study, we sequenced DNA samples from 70 animals from seven indigenous cattle breeds, generating about two terabytes of pair-end reads with an average coverage of 14X. The sequencing data were pre-processed and mapped to the cattle reference genome (ARS-UCD1.2) with an alignment rate of 99.2%. Finally, the variant calling process produced approximately 35 million high-quality SNPs. These data provide a deeper understanding of the genetic landscape, facilitate the identification of causal mutations, and enable the exploration of evolutionary patterns to assist cattle improvement and sustainable utilization, particularly in the face of unpredictable climate changes.

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