A Convenient Synthesis of D,L-Selenomethionine

文献类型: 外文期刊

第一作者: Ran, X. G.

作者: Ran, X. G.;Cao, D. R.;Wang, L. Y.;Ran, X. G.;Lin, Y. C.

作者机构:

关键词: amino acids;alpha-bromo-gamma-butyrolactone;heterocycles;selenium;reduction

期刊名称:POLISH JOURNAL OF CHEMISTRY ( 影响因子:0.393; 五年影响因子:0.38 )

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年卷期:

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收录情况: SCI

摘要: A convenient synthesis of D,L-selenomethionine from alpha-bromo-gamma-butyrolactone in 4 steps and 26% overall yield has been described.Selenomethionine,an unnatural amino acid,has got increasing importance because it has been expected to be a reagent protecting human systems against oxidation,radiations,cancer,aging and related diseases,and is also a source of selenium in the diets of both animals and humans [1].Numerous synthetic methods leading to selenomethionine have been reported [2-9].

分类号: O6

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