A Comparative Study on the Composition and Structure of Human Milk Phospholipids and its Natural Resources: Based on a Similarity Evaluation Model

文献类型： 外文期刊

第一作者： Zhu, Huiquan

作者： Zhu, Huiquan;Wang, Xiaodan;Zhang, Yumeng;Zhang, Shuwen;Wang, Yunna;Pang, Xiaoyang;Lv, Jiaping;Zhu, Huiquan;Fauconnier, Marie-Laure;Zhang, Hong;Xu, Xuebing;Guo, Ruihua;Zhang, Wenyuan;Zhu, Huiquan;Wang, Yunna

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关键词： Human milk; Phospholipid; Similarity index; Evaluation model

期刊名称：FOOD CHEMISTRY （ 影响因子：8.5； 五年影响因子：8.2 ）

ISSN： 0308-8146

年卷期： 2024 年 460 卷

页码：

收录情况： SCI

摘要： Human milk phospholipids (HMPLs) play an indispensable role in the neurodevelopment and growth of infants. In this study, a total of 37 phospholipid fatty acid (PLFA) species and 139 phospholipid molecular species were detected from human milk and other natural phospholipid sources (including 5 animal-derived species and 2 plant species). Moreover, a similarity evaluation model for HMPLs was established, including phospholipid classes, PLFAs, and phospholipid molecular species, to evaluate their natural substitutes. The closest scores for HMPL substitute in these three dimensions was 0.89, 0.72, and 0.77, which belonged to mare milk, goat milk, and camel milk, respectively. The highest comprehensive similarity score was obtained by camel milk at 0.75, while the lowest score was observed in soybean phospholipid (0.22). Therefore, these results not only monitored the stereochemical structure of HMPLs and their substitutes, but also further provided new insights for the development of infant formulae.

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