文献类型： 外文期刊
第一作者： Sun, Fangnan
作者： Sun, Fangnan;Deng, Yaxin;Liu, Yuan;Zhao, Lingxia;Zhang, Lida;Ma, Xiaosong;Yu, Shunwu
作者机构：
关键词： Rice; protein-protein interaction; interactome; protein docking
期刊名称：GENETICS AND MOLECULAR BIOLOGY （ 影响因子：2.1； 五年影响因子：2.2 ）
ISSN： 1415-4757
年卷期： 2024 年 47 卷 1 期
页码：
收录情况： SCI
摘要： Comprehensive protein -protein interaction (PPI) maps are critical for understanding the functional organization of the proteome, but challenging to produce experimentally. Here, we developed a computational method for predicting PPIs based on protein docking. Evaluation of performance on benchmark sets demonstrated the ability of the docking-based method to accurately identify PPIs using predicted protein structures. By employing the docking-based method, we constructed a structurally resolved PPI network consisting of 24,653 interactions between 2,131 proteins, which greatly extends the current knowledge on the rice protein -protein interactome. Moreover, we mapped the trait-associated single nucleotide polymorphisms (SNPs) to the structural interactome, and computationally identified 14 SNPs that had significant consequences on PPI network. The protein structural interactome map provided a resource to facilitate functional investigation of PPI-perturbing alleles associated with agronomically important traits in rice.
分类号：
- 相关文献
作者其他论文 更多>>
-
A fast and efficient virtual screening and identification strategy for helix peptide binders based on finDr webserver: A case study of bovine serum albumin (BSA)
作者：Bu, Jiarui;Luo, Na;Liu, Yuan;Luo, Chuping;Zhang, Xiao;Bu, Jiarui;Luo, Na;Shen, Cheng;Xu, Chongxin;Zhu, Qing;Chen, Chengyu;Xie, Yajing;Liu, Xianjin;Liu, Yuan;Zhang, Xiao
关键词：Virtual screening; Affinity identification; Molecular simulations
-
Impact of Hormone on Growth and GA3 Regulation of Anthocyanin Biosynthesis in Suspension-Culture Cells of Cyclocarya paliurus
作者：Pan, Chuanqing;Liu, Yuan;Chen, Jiguang;Yin, Zhongping;Tang, Daobang
关键词：anthocyanin; Cyclocarya paliurus; gibberellin A(3); multi-omics; plant cell culture
-
Synergistic use of stay-green traits and UAV multispectral information in improving maize yield estimation with the random forest regression algorithm
作者：Liu, Yuan;Meng, Lin;Nie, Chenwei;Liu, Yadong;Song, Yang;Jin, Xiuliang;Liu, Yuan;Fan, Kaijian;Meng, Lin;Nie, Chenwei;Liu, Yadong;Song, Yang;Jin, Xiuliang;Cheng, Minghan
关键词：UAV multispectral; Maize yield; Stay-Green Index (SGI); Machine learning; Remote sensing
-
Novel Umami Peptides from Lentinula edodes: Evaluation of the Umami Enhancing Effect Using Biosensors and Molecular Simulation
作者：Zhao, Shilong;Cui, Zhiyong;Zheng, Yuqian;Yu, Yanyang;Zhou, Changlin;Zhou, Quanlong;Zhang, Amin;Guo, Xueqian;Liu, Yuan;Wang, Wenli;Zhao, Shilong;Wang, Shengnan;Xu, Changhua;Liu, Yuan;Yang, Yan;Luo, Zisheng
关键词：
Lentinula edodes ; umami peptide; umami enhancing effect; biosensor; moleculardynamics simulation -
Maize biomass estimation by integrating spectral, structural, and textural features from unmanned aerial vehicle data
作者：Meng, Lin;Yin, Dameng;Jin, Xiuliang;Meng, Lin;Ming, Bo;Nie, Chenwei;Fang, Liang;Zhou, Lili;Xin, Jiangfeng;Xue, Beibei;Liang, Zhongyu;Guo, Huirong;Yin, Dameng;Jin, Xiuliang;Meng, Lin;Liu, Yuan;Nie, Chenwei
关键词：Unmanned Aerial Vehicle (UAV); Aboveground biomass (AGB); Organ biomass; Maize; Ensemble learning
-
An anti-idiotypic single domain antibody as Cry2Aa toxin mimotope and analysis of its binding region through molecular docking
作者：Lin, Manman;Han, Guangjie;Li, Chuanming;Huang, Lixin;Liu, Qin;Zhang, Nan;Xia, Yang;Lu, Yurong;Xu, Jian;Liu, Xianjin;Liu, Yuan;Lin, Johnson
关键词：Cry2Aa toxin; Anti-idiotypic antibody; Single-domain antibody; Epitopes; Mimotope; Molecular docking
-
Unraveling Fish Community Diversity and Structure in the Yellow Sea: Evidence from Environmental DNA Metabarcoding and Bottom Trawling
作者：Zhang, Jinyong;Liu, Yuan;Ye, Jinqing;Li, Hongjun;Cui, Xiaoyu;Lin, Lin;Zhang, Weiyue
关键词：eDNA metabarcoding; fish community; diversity; bottom trawling; Yellow Sea
