Commensal lifestyle regulated by a negative feedback loop between Arabidopsis ROS and the bacterial T2SS

文献类型： 外文期刊

第一作者： Entila, Frederickson

作者： Entila, Frederickson;Han, Xiaowei;Tsuda, Kenichi;Entila, Frederickson;Schulze-Lefert, Paul;Tsuda, Kenichi;Han, Xiaowei;Tsuda, Kenichi;Han, Xiaowei;Tsuda, Kenichi;Mine, Akira;Mine, Akira

作者机构：

期刊名称：NATURE COMMUNICATIONS （ 影响因子：16.6； 五年影响因子：17.0 ）

ISSN：

年卷期： 2024 年 15 卷 1 期

页码：

收录情况： SCI

摘要： Despite the plant health-promoting effects of plant microbiota, these assemblages also comprise potentially detrimental microbes. How plant immunity controls its microbiota to promote plant health under these conditions remains largely unknown. We find that commensal bacteria isolated from healthy Arabidopsis plants trigger diverse patterns of reactive oxygen species (ROS) production dependent on the immune receptors and completely on the NADPH oxidase RBOHD that selectively inhibited specific commensals, notably Xanthomonas L148. Through random mutagenesis, we find that L148 gspE, encoding a type II secretion system (T2SS) component, is required for the damaging effects of Xanthomonas L148 on rbohD mutant plants. In planta bacterial transcriptomics reveals that RBOHD suppresses most T2SS gene expression including gspE. L148 colonization protected plants against a bacterial pathogen, when gspE was inhibited by ROS or mutation. Thus, a negative feedback loop between Arabidopsis ROS and the bacterial T2SS tames a potentially detrimental leaf commensal and turns it into a microbe beneficial to the host.

分类号：

  • 相关文献
作者其他论文 更多>>

微信小程序