Whole-genome sequencing of multidrug-resistant Klebsiella pneumoniae with capsular serotype K2 isolates from mink in China
文献类型： 外文期刊
第一作者： Sun, Na
作者： Sun, Na;Guo, Li;Liu, Liming;San, Zhihao;Zhao, Cuiqing;Zhao, Lifeng;Chen, Qiang;Yang, Yong;Tong, Mingwei;Cheng, Yuening;Wang, Guisheng
作者机构：
关键词： Klebsiella pneumoniae; Mink; K2 serotype; Resistance genes; Virulence genes
期刊名称：BMC VETERINARY RESEARCH （ 影响因子：2.3； 五年影响因子：2.6 ）
ISSN：
年卷期： 2024 年 20 卷 1 期
页码：
收录情况： SCI
摘要： Background Klebsiella pneumoniae is a zoonotic opportunistic pathogen, and also one of the common pathogenic bacteria causing mink pneumonia. The aim of this study was to get a better understanding of the whole-genome of multi-drug resistant Klebsiella pneumoniae with K2 serotype in China. This study for the first time to analyze Gene Ontology (GO) enrichment, Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment, resistance and virulence genes of Klebsiella pneumoniae in mink. Results The isolate was Klebsiella pneumoniae with serotype K2 and ST6189 by PCR method. The string test was positive and showed high mucus phenotype. There was one plasmid with IncFIB replicons in the genome. The virulence factors including capsule, lipopolysaccharide, adhesin, iron uptake system, urease, secretory system, regulatory gene (rcsA, rcsB), determinants of pili adhesion, enolase and magnesium ion absorption related genes. The strain was multi-drug resistant. A total of 26 resistance genes, including beta-lactam, aminoglycosides, tetracycline, fluoroquinolones, sulfonamides, amide alcohols, macrolides, rifampicin, fosfomycin, vancomycin, diaminopyrimidines and polymyxin. Multidrug-resistant efflux protein AcrA, AcrB, TolC, were predicted in the strain. Conclusion It was the first to identify that serotype K2 K. pneumonia with ST6189 isolated from mink in China. The finding indicated that hypervirulent and multi-drug resistant K. pneumoniae was exist in Chinese mink. The whole-genome of K. pneumoniae isolates have importance in mink farming practice.
分类号：
- 相关文献
作者其他论文 更多>>
-
Identification of QTLs and candidate genes for water-soluble protein content in soybean seeds
作者：Zhang, Xujuan;Wang, Fengmin;Chen, Qiang;Zhao, Qingsong;Zhao, Tiantian;Hu, Xuejie;Liu, Luping;Qi, Jin;Zhang, Mengchen;Yang, Chunyan;Qin, Jun;Zhang, Xujuan;Hu, Xuejie;Qiao, Yake;Zhao, Tiantian;Qi, Jin
关键词：Soybean; WSP; QTL; Candidate gene mining
-
Baicalin ameliorates the gut barrier function and intestinal microbiota of broiler chickens
作者：Wan, Shuangxiu;Mao, Xiaoxia;Li, Hongquan;Sun, Panpan;Yin, Wei;Fan, Kuohai;Sun, Na;Wan, Shuangxiu;Zhu, Lin;Wang, Linzheng;Hao, Zhili;Zhang, Hailong;Li, Beibei;Nie, Wansen;Li, Zongjie
关键词：baicalin; broiler; immune homeostasis; gut barrier; gut microbiota
-
Estimating reference crop evapotranspiration using optimized empirical methods with a novel improved Grey Wolf Algorithm in four climatic regions of China
作者：Dong, Juan;Xing, Liwen;Cui, Ningbo;Guo, Li;Liang, Chuan;Zhao, Lu;Wang, Zhihui;Gong, Daozhi
关键词：Empirical parameter; Intelligence optimization algorithm; Radiation -based method; Humidity -based method; Temperature -based method
-
Cancer cell membrane proteins-encapsulated nanovaccine enhances cancer immunotherapy and prevention by provoking antigen-specific cellular immunity via the dendritic cell-targeted delivery
作者：Luo, Xingyu;Ma, Rongying;Fu, Zhaoming;Liu, Zuwei;Su, Qianhong;Fu, Huiling;Yang, Yong;Chen, Xiaolu;Xue, Wei
关键词：Metal-phenolic networks; Cancer nanovaccine; Mannose receptor; Cytotoxic T cell; Cancer immunotherapy
-
Estimating reference crop evapotranspiration using improved convolutional bidirectional long short-term memory network by multi-head attention mechanism in the four climatic zones of China
作者：Dong, Juan;Xing, Liwen;Cui, Ningbo;Zhao, Lu;Guo, Li;Wang, Zhihui;Tan, Mingdong;Du, Taisheng;Gong, Daozhi
关键词：Hybrid deep learning model; Multivariate Adaptive Regression Splines; Empirical model; Limited meteorological input; Cross-validation strategy
-
Optimizing cotton yield through appropriate irrigation water salinity: Coordinating above- and below-ground growth and enhancing photosynthetic capacity
作者：Ma, Zhanli;Liu, Jian;Wen, Yue;Zhang, Jinzhu;Li, Wenhao;He, Jing;Ma, Jiaying;Liang, Yonghui;Wang, Zhenhua;Ma, Zhanli;Liu, Jian;Wen, Yue;Zhang, Jinzhu;Li, Wenhao;He, Jing;Ma, Jiaying;Liang, Yonghui;Wang, Zhenhua;Ma, Zhanli;Liu, Jian;Wen, Yue;Zhang, Jinzhu;Li, Wenhao;He, Jing;Ma, Jiaying;Liang, Yonghui;Wang, Zhenhua;Yin, Feihu;Guo, Li
关键词：Irrigation water salinity; Cotton productivity; Coordinated growth; Photosynthetic capacity; Mulched drip irrigation
-
The TaSnRK1-TabHLH489 module integrates brassinosteroid and sugar signalling to regulate the grain length in bread wheat
作者：Lyu, Jinyang;Sun, Na;Yang, Fan;Li, Xuepeng;Mu, Junyi;Zhou, Runxiang;Zheng, Guolan;Yang, Xin;Zhang, Chenxuan;Han, Chao;Xia, Guang-Min;Fan, Min;Bai, Ming-Yi;Wang, Dongzhi;Xiao, Jun;Li, Genying;Xiao, Jun;Xiao, Jun
关键词：wheat grain length; brassinosteroid; sugar; TabHLH489; SnRK1
