Identification of a novel angiogenin inhibitor 1 and its association with hyaluronidase of Streptococcus suis serotype 2
文献类型: 外文期刊
第一作者: Chen, Huanchun
作者: Chen, Huanchun;Wo, Tao;Yuan, Fangyan;Chang, Haitao;Chen, Guangping;Tan, Chen;Chen, Huanchun;Bei, Weicheng;Zhang, Lin
作者机构:
关键词: Nervous System: Neural Coordination;Infection;Enzymology: Biochemistry and Molecular Biophysics
期刊名称:MICROBIAL PATHOGENESIS ( 影响因子:3.738; 五年影响因子:3.663 )
ISSN:
年卷期:
页码:
收录情况: SCI
摘要: To characterize the role of hyaluronidase (Hyl) of Streptococcus sins serotype 2 (S sins 2), the hylA gene that encodes Hyl was cloned, expressed and purified A murine brain cDNA library was used to screen for interacting proteins of Hyl Employing the yeast two-hybrid system, a novel murine ribonuclease, angiogenin inhibitor 1 (AI1), which shares 93% homology with porcine AI1, was shown to interact with Hyl in yeast Through co-immunoprecipitation assays, the interaction between AI1 and Hyl was further confirmed Transcription and translation products of the identified cDNA were detected in both normal cells and S suis 2-infected cells AI1 was found to localize mainly in the cytoplasm of 293T cells. These results suggested that the identified protein AI1 might be involved in the pathogenesis of meningitis through interaction with Hyl of S sins 2
分类号: R3
- 相关文献
作者其他论文 更多>>
-
Polymerization of beneficial plant height QTLs to develop superior lines which can achieving hybrid performance levels
作者:Kang, Congbin;Hao, Yichen;Sun, Mingfei;Li, Mengyao;Tian, Ziang;Zhao, Yajie;Zhou, Chao;Zhao, Xiang Yu;Zhang, Xian Sheng;Yang, Xuerong;Liu, Hongjun;Zhang, Lin;Dong, Ling;Liu, Xianjun;Zeng, Xing;Sun, Yanjie;Cao, Shiliang;Luebberstedt, Thomas
关键词:Heterosis; Complex agronomic traits; Plant height; Molecular design; Pyramiding QTL line (PQL); Maize
-
The role of the nitrate transporter NRT1.1 in plant iron homeostasis and toxicity on ammonium
作者:Li, Guangjie;Zhang, Lin;Wang, Yanqin;Li, Yan;Wang, Zhaoyue;Shi, Weiming;Kronzucker, Herbert J.;Kronzucker, Herbert J.;Chen, Gui
关键词:Ammonium toxicity; Iron; Nitrate; NRT1.1; Root growth
-
Rosaceae phylogenomic studies provide insights into the evolution of new genes
作者:Jiang, Lan;Lyu, Kun;Li, Xiaoxu;Cao, Yunpeng;Cao, Yunpeng;Li, Zhiyuan;Qi, Wang;Wang, Han;Zhang, Lin
关键词:Rosa banksiae; Gap-free genome; Rosaceae; Phenotype; Evolutionary patterns
-
Volatile flavor and digestion behavior of peanut protein-based patties: Role of lipid type and oil phase incorporation method
作者:Chen, Ying;Zhang, Lin;Wang, Weifei
关键词:Plant-based patties; Acylglycerol; Volatile flavor; Digestion behavior
-
The Transcription Factor ZmMYBR24 Gene Is Involved in a Variety of Abiotic Stresses in Maize (Zea mays L.)
作者:Bao, Liangliang;Sun, Wen;Wang, Jiaxin;Zhou, Yuyang;Wang, Jiahao;Wang, Qi;Zhou, Yu;Zhang, Lin;Wang, Zhenhua;Li, Chunxiang;Di, Hong;Sun, Dequan;Lin, Hong;Fan, Jinsheng
关键词:maize; ZmMYBR24 gene; adversity stress; functional validation; RNA-seq
-
Phenolic Acid and Flavonoid Content Analysis with Antioxidant Activity Assessment in Chinese C. pi. Shen Honey
作者:Qi, Ningxin;Zhao, Wen;Xue, Chenghua;Zhang, Lin;Hu, Han;Jin, Yue;Xue, Xiaofeng;Chen, Rui;Zhang, Jinzhen
关键词:phenolic compound; antioxidant activities;
C. pi. Shen honey; different botanic origins -
EGDB: A comprehensive multi-omics database for energy grasses and the epigenomic atlas of pearl millet
作者:Luo, Lin;Qu, Qi;Zhang, Lin;Jiang, Dingkun;Zhu, Wenjun;Lu, Guodong;Zhu, Fangjie;Xiao, Jiajing;Lin, Dongmei;Chen, Hao;Luo, Yuan;Chen, Jiaming;Lin, Hui;Shao, Ensi;Lin, Zhanxi;Li, Jinhui;Lu, Peitao;Yan, Haidong;Jin, Yarong;Huang, Linkai;Xun, Lulu
关键词: