Genomic selection, gene editing, and reproductive biotechnology: a triad for the improvement of native buffalo breeds in a developing country perspective like Pakistan
文献类型: 外文期刊
第一作者: Muner, Raja Danish
作者: Muner, Raja Danish;Babar, Masroor Ellahi;Muner, Raja Danish;Bi, Yanzhen;Abbas, Ghulam;Maqbool, Babar;Saleem, Ali Haider;Saleem, Ali Haider;Farooq, Farhan;Ullah, Qudrat;Moaeen-ud-Din, Muhammad
作者机构:
关键词: Buffalo; SNP Chip; Genomic Selection; Gene Editing; Reproductive Biotechnology
期刊名称:TROPICAL ANIMAL HEALTH AND PRODUCTION ( 影响因子:1.7; 五年影响因子:1.8 )
ISSN: 0049-4747
年卷期: 2025 年 57 卷 2 期
页码:
收录情况: SCI
摘要: Pakistan is the 2nd largest country in buffalo population in the world. The current population of buffalo in Pakistan is 45.0 million heads whereas the current world buffalo population is 200 million heads. Pakistan is home to one of the best buffalo breeds in the world i.e., Nili, Ravi, Nili-Ravi, Kundi, and Azi Khaili. Moreover, Pakistan is ranked 2nd largest buffalo-milk-producing country in the world. Keeping in consideration, the tremendous role and importance of buffalo, the current study aims to provide a comprehensive overview of the important genetic studies conducted up till now and the need to apply the latest genomic tools, gene editing, and reproductive biotechnologies for the improvement of these native buffalo breeds. The current research is limited to a few diversity studies, basic phylogenetics, evolution, and genetic characterization using only a few loci and phenotypic studies of limited productive traits. The current picture is gloomy as proper genetic characterization and diversity study of these breeds has never been made using reliable, accurate, and advanced genomic techniques. In a developing country like Pakistan where there is no comprehensive data collection coupled with scattered farming without any organized breeding system; genomic selection, gene editing, and application of advanced reproductive biotechnology techniques are the most promising techniques for rapid and sustainable development in the productive and reproductive potential of our Black Gold. Advancement in the methods of genotyping using commercially available SNP Chips at affordable prices along with improvements in reproductive biotechnology and genome editing techniques will provide the framework for the true genetic exploration and optimal utilization of precious native buffalo breeds potential. Conclusively, these techniques have great potential to revolutionize the world's buffalo population.
分类号:
- 相关文献
作者其他论文 更多>>
-
Application of Multiple Base-Editing Mediated by Polycistronic tRNA-gRNA-Processing System in Pig Cells
作者:Zhao, Wudi;Huang, Guobin;Gu, Hao;Bi, Yanzhen;Ren, Hongyan;Zhao, Wudi;Zhu, Xiangxing;Huang, Guobin;Tang, Dongsheng
关键词:base editing; CD163; endogenous tRNA self-processing system; genetic improvement; MSTN; pig
-
Targeting Nrf2/KEAP1 signaling pathway using bioactive compounds to combat mastitis
作者:Khan, Muhammad Zahoor;Li, Liangliang;Zhan, Yandong;Huang, Binjiang;Liu, Xiaotong;Kou, Xiyan;Wang, Tongtong;Wang, Changfa;Khan, Adnan;Qadeer, Abdul;Ullah, Qudrat;Alzahrani, Khalid J.;Zahoor, Muhammad
关键词:mastitis; inflammation; immunity; oxidative stress; antioxidants; bioactive compounds; Nrf2/Keap1 signaling pathway
-
Overexpression of miR-192 Inhibits In Vitro Porcine Embryo Development by Inducing Oxidative Stress Damage and Impairing Mitochondrial Function
作者:He, Fan;Li, Mingguo;Qi, Mengfan;Fu, Binbin;Zhang, Huapeng;Li, Qingchun;Huang, Tao;Li, Mingguo;Chen, Fan;Bi, Yanzhen;Zhou, Rong;Huang, Tao
关键词:pig; miR-192; early embryo development
-
Nuclearporin subcomplex Nup98/Rae1 is vital for maternal-to-zygotic transition during early embryonic development
作者:Luo, Anfeng;Gu, Hao;Qi, Mengfan;Pan, Kaixin;Zhou, Changfan;Zeng, Wei;Liu, Song;Ren, Hongyan;Bi, Yanzhen;Chen, Fan;Bi, Yanzhen;Ali, Akhtar
关键词:Nup98; Rae1; Early embryonic development; Zygotic genome activation; Histone modification
-
Comparative assessment of biochar and vermicompost on chromium bioavailability and stress alleviation in tomato (Solanum lycopersicum)
作者:Kabir, Jamaluddin;Farooq, Muhammad Ansar;Parvez, Shumaila;Din, Aamir Alaud;Farooq, Muhammad Ansar;Abbas, Ghulam;Xu, Minggang;Xu, Minggang;Abrar, Muhammad Mohsin;Abrar, Muhammad Mohsin
关键词:Biochar; Chromium; Iron enriched biochar; Tomato; Vermicompost
-
Target silencing of porcine SPAG6 and PPP1CC by shRNA attenuated sperm motility
作者:Ren, Hongyan;Zhang, Yandi;Bi, Yanzhen;Wang, Heng;Zhao, Pengxiang;Fang, Guijie;Zhao, Pengxiang;Fang, Guijie
关键词:SPAG6; PPP1CC; Sperm quality; Pig
-
Enhancing bovine immune, antioxidant and anti-inflammatory responses with vitamins, rumen-protected amino acids, and trace minerals to prevent periparturient mastitis
作者:Khan, Muhammad Zahoor;Huang, Bingjian;Kou, Xiyan;Chen, Yinghui;Liang, Huili;Chai, Wenqiong;Wang, Changfa;Huang, Bingjian;Ullah, Qudrat;Khan, Ibrar Muhammad;Khan, Adnan
关键词:periparturient period; mastitis; dairy cattle; immunity; antioxidant status; antiinflammation; amino acids; trace minerals