Elucidating the Bioinspired Synthesis Process of Magnetosomes-Like Fe3O4 Nanoparticles
文献类型: 外文期刊
第一作者: Mao, Yu
作者: Mao, Yu;Liu, Jizi;Zhang, Kai;Gu, Ning;Mao, Yu;Sun, Jianfei;Zhao, Yifan;An, Yuan;Wu, Lihe;Feng, Haikao;Li, Yan;Gu, Ning;Chen, Bo;Chen, Ruipeng;Huang, Xiao;Huang, Xiao
作者机构:
关键词: bioinspired synthesis; biomedical nanomaterials; iron oxide nanoparticles; magnetosomes-like; partial oxidation
期刊名称:SMALL ( 影响因子:13.3; 五年影响因子:13.2 )
ISSN: 1613-6810
年卷期: 2024 年 20 卷 21 期
页码:
收录情况: SCI
摘要: Iron oxide nanoparticles are a kind of important biomedical nanomaterials. Although their industrial-scale production can be realized by the conventional coprecipitation method, the controllability of their size and morphology remains a huge challenge. In this study, a kind of synthetic polypeptide Mms6-28 which mimics the magnetosome protein Mms6 is used for the bioinspired synthesis of Fe3O4 nanoparticles (NPs). Magnetosomes-like Fe3O4 NPs with uniform size, cubooctahedral shape, and smooth crystal surfaces are synthesized via a partial oxidation process. The Mms6-28 polypeptides play an important role by binding with iron ions and forming nucleation templates and are also preferably attached to the [100] and [111] crystal planes to induce the formation of uniform cubooctahedral Fe3O4 NPs. The continuous release and oxidation of Fe2+ from pre-formed Fe2+-rich precursors within the Mms6-28-based template make the reaction much controllable. The study affords new insights into the bioinspired- and bio-synthesis mechanism of magnetosomes.
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