Dose-dependent effects of extracted microcystins on embryonic development, larval growth and histopathological changes of southern catfish (Silurus meridionalis)

文献类型: 外文期刊

第一作者: Xie, Ping

作者: Xie, Ping;Li, Dapeng;Li, Li;Tang, Rong;Lei, Hehua;Zhang, Xuezhen;Xie, Ping;Wang, Weimin;Li, Dapeng;Li, Li;Tang, Rong;Shi, Zechao

作者机构:

关键词: microcystins;crude extract;southern catfish;embryonic development;larval growth;histopathological changes;CARP CYPRINUS-CARPIO;ZEBRAFISH DANIO-RERIO;CYANOBACTERIAL TOXINS;CARASSIUS-AURATUS;ORYZIAS-LATIPES;CRUDE EXTRACTS;LR;FISH;TOXICITY;ACCUMULATION

期刊名称:TOXICON ( 影响因子:3.033; 五年影响因子:2.689 )

ISSN:

年卷期:

页码:

收录情况: SCI

摘要: A laboratory toxic experiment was conducted to examine dose-dependent effects of extracted microcystins (MCs) on embryonic development, larval growth and histopathological changes of southern catfish (Silurus meridionalis). Fertilized eggs were incubated in solutions with four concentrations of MCs (0, 1, 10, 100 mu g MC-LReq l(-1)). Higher MCs retarded egg development (2-10 h delays) and larval growth, reduced hatching rate (up to 45%), and caused high malformation rate (up to 15%) and hepatocytes damage (characterized by disorganization of cell structure and a loss of adherence between hepatocytes, cellular degeneration with vacuolar hepatocytes and marginal nuclei, even hepatocellular necrosis). A 10 mu g MC-LReql(-1) is close to a high concentration in natural cyanobacterial blooms, suggesting a possible existence of such toxic effects in eutrophic waters. (c) 2007 Elsevier Ltd. All rights reserved.

分类号: R9

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