Brominated aliphatic hydrocarbons and sterols from the sponge Xestospongia testudinaria with their bioactivities

文献类型： 外文期刊

第一作者： Zhou, Xuefeng

作者： Zhou, Xuefeng;Lin, Xiuping;Yang, Bin;Yang, Xianwen;Liu, Yonghong;Lu, Yanan

作者机构：

关键词： Anti-acetylcholinesterase;Brominated aliphatic hydrocarbons;Mutafuran H;Sterols;Toxicity;Xestospongia testudinaria

期刊名称：CHEMISTRY AND PHYSICS OF LIPIDS （ 影响因子：3.329； 五年影响因子：3.4 ）

ISSN：

年卷期：

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收录情况： SCI

摘要： Four brominated aliphatic hydrocarbons (1-4), including a novel brominated ene-tetrahydrofuran named as mutafuran H (1), and five sterols (5-9) were isolated from the South China Sea sponge Xestospongia testudinaria. The structure of 1 was determined on the basis of NMR (~1H, ~(13)C NMR, HSQC, HMBC, ~1H-~1H COSY, and NOESY), MS, and optical rotation analysis. Known compounds were identified by comparison of their NMR data with those reported in the literature. Compounds 1-4, and 6-9 were evaluated for their toxicity against Artemia salina larvae, and anti-acetylcholinesterase activity.

分类号： Q54

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