Xylitol production by Candida tropicalis from corn cob hemicellulose hydrolysate in a two-stage fed-batch fermentation process

文献类型： 外文期刊

第一作者： Meng, Xiumei

作者： Meng, Xiumei;Li, Minghua;Du, Fangling;Diao, Enjie

作者机构：

关键词： Candida tropicalis;Fermentation;Hemicellulose hydrolysate;Xylitol

期刊名称：JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY （ 影响因子：3.174； 五年影响因子：3.137 ）

ISSN：

年卷期：

页码：

收录情况： SCI

摘要： Xylitol, a sugar alcohol widely used in food and pharmaceutical industries, can be produced through biological reduction of xylose present in hemicellulose hydrolysates by Candida tropicalis. However, the aeration rate and by-products originating from hemicellulose hydrolysis strongly inhibit the production of xylitol in a fermentation process. A two-stage fed-batch fermentation system was developed to reduce these inhibitory effects and to improve xylitol production from corn cob hemicellulose hydrolysates by C. tropicalis. Results: Results of batch fermentations indicated that high xylitol production could be obtained from C. tropicalis at an initial xylose concentration of 80 g L ~(-1) in corn cob hydrolysate medium at an aeration rate of 0.4 vvm at the micro-aeration stage. In the two-stage fed-batch fermentation process, 96.5 g L ~(-1) xylitol was obtained after 120 h, giving a yield of 0.83 g g ~(-1) and a productivity of 1.01 g L ~(-1) h ~(-1), which were 12.16% and 65.57% higher than those in a batch fermentation. Conclusion: High xylitol production can be achieved in a two-stage fed-batch fermentation process, in which the negative effects of aeration rate and inhibitory compounds on xylitol formation can be considerably reduced.

分类号： Q81

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